Journal of Associated Medical SciencesBackground: Low voltage, high frequency electrochemotherapy (LVHF ECT) has recently been explored as a method to enhance the permeability of cell membranes to non-permanent chemotherapeutic agents.
Zeinab Shankayi +2 more
doaj +1 more source
Dynamics of membrane lipid domains in neuronal cells differentiated in culture1
Journal of Lipid Research, 2003 Treatment with methyl-β-cyclodextrin (MCD) induced a time- and dose-dependent efflux of cholesterol, sphingolipids, and phosphatidylcholine (PC) from cerebellar neurons differentiated in culture. With a “mild” treatment, the loss of cell lipids induced a
Elena Ottico +6 more
doaj +1 more source
Frontiers in Nutrition, 2021 This study was performed to determine the antifungal activity of loquat (Eriobotrya japonica Lindl) leaf extract (LLE) against the citrus postharvest pathogen Penicillium digitatum (P. digitatum).
Yuting Shen +9 more
doaj +1 more source
Decision trees to characterise the roles of permeability and solubility on the prediction of oral absorption. [PDF]
, 2015 Oral absorption depends on many physiological, physiochemical and formulation factors. Two important properties that govern oral absorption are in vitro permeability and solubility, which are commonly used as indicators of human intestinal absorption ...
Newby, Danielle +6 more
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
CO2 Permeability of Biological Membranes and Role of CO2 Channels
Membranes, 2017 We summarize here, mainly for mammalian systems, the present knowledge of (a) the membrane CO2 permeabilities in various tissues; (b) the physiological significance of the value of the CO2 permeability; (c) the mechanisms by which membrane CO2 ...
Volker Endeward +3 more
doaj +1 more source
Identification of senescence and death in Emiliania huxleyi and Thalassiosira pseudonana: Cell staining, chlorophyll alterations, and dimethylsulfoniopropionate (DMSP) metabolism [PDF]
, 2012 We measured membrane permeability, hydrolytic enzyme, and caspase-like activities using fluorescent cell stains to document changes caused by nutrient exhaustion in the coccolithophore Emiliania huxleyi and the diatom Thalassiosira pseudonana, during ...
Berges, John A. +19 more
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Femtosecond optoinjection of intact tobacco BY-2 cells using a reconfigurable photoporation platform. [PDF]
PLoS ONE, 2013 A tightly-focused ultrashort pulsed laser beam incident upon a cell membrane has previously been shown to transiently increase cell membrane permeability while maintaining the viability of the cell, a technique known as photoporation.
Claire A Mitchell +7 more
doaj +1 more source
Structure determination of membrane-located complexes: Aquaporin 8 and YscC secretin [PDF]
, 2011 A biological membrane is key to the life of a cell. In all living cells a biological membrane separates a inner life and an outer environment. Plasma membrane has many functions such as responding to external signals and transmitting them into the cell,
Kowal, Julia
core +1 more source