Results 71 to 80 of about 377,298 (310)

The apical submembrane cytoskeleton participates in the organization of the apical pole in epithelial cells [PDF]

, 1997
In a previous publication (Rodriguez, M.L., M. Brignoni, and P.J.I. Salas. 1994. J. Cell Sci. 107: 3145-3151), we described the existence of a terminal web-like structure in nonbrush border cells, which comprises a specifically apical cytokeratin ...
Ana L. Viciana, Viciana, A. L., Salas, Pedro J.I, Dora E. Vega-Salas, Hauri, H. P., Hans-Peter Hauri, Marcelo L. Rodriguez, Rodriguez, M. L., Hauri, Hans-Peter, Vega-Salas, D. E., Salas, P. J., Pedro J.I. Salas, Rodriguez, Marcelo L, Vega-Salas, Dora E, Viciana, Ana L   +14 more
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Polyelectrolyte multilayer films as backflushable nanofiltration membranes with tunable hydrophilicity and surface charge [PDF]

, 2010
A diverse set of supported polyelectrolyte multilayer (PEM) membranes with controllable surface charge, hydrophilicity, and permeability to water and salt was designed by choosing constituent polyelectrolytes and by adjusting conditions of their ...
Shan, Wenqian, L, Merlin, Bruening, Bacchin, Patrice, Aimar, Pierre, Tarabara, Volodymyr V., V, Volodymyr, Tarabara, Bruening, Merlin L.   +6 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

A Barrier to Entry: Examining the Bacterial Outer Membrane and Antibiotic Resistance

Applied Sciences, 2023
Gram-negative bacteria can resist antibiotics by changing the permeability via their outer membrane. These bacteria have a complex cell envelope that incorporates an outer membrane separating the periplasm from the external environment.
Ishan Ghai
doaj   +1 more source

Preparative scale production of functional mouse aquaporin 4 using different cell-free expression modes

, 2010
The continuous progress in the structural and functional characterization of aquaporins increasingly attracts attention to study their roles in certain mammalian diseases.
Volker Dötsch, Lian, Jiazhang, Kaldenhoff Ralf, Dötsch, Volker, Frank Bernhard, Xiangcheng Zhu, Cen, Peilin, Dötsch Volker, Lei Kai, Zhinan Xu, Xu, Zhinan, Peilin Cen, Kai Lei, Kai, Lei, Cen Peilin, Kaldenhoff, Ralf, Xu Zhinan, Zhu Xiangcheng, Ralf Kaldenhoff, Lian Jiazhang, Jiazhang Lian, Bernhard, Frank, Zhu, Xiangcheng, Bernhard Frank   +23 more
core   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Effects of aquaporin-lipid molar ratio on the permeability of an aquaporin Z-phospholipid membrane system.

PLoS ONE, 2020
Aquaporins are water-permeable membrane-channel proteins found in biological cell membranes that selectively exclude ions and large molecules and have high water permeability, which makes them promising candidates for water desalination systems.
Hyunki Kim, Byung Ho Lee, Moon-Ki Choi, Sangjae Seo, Moon Ki Kim   +4 more
doaj   +1 more source

Antibacterial and Antibiofilm Activities of Chlorogenic Acid Against Yersinia enterocolitica

Frontiers in Microbiology, 2022
Nowadays, developing new and natural compounds with antibacterial activities from plants has become a promising approach to solve antibiotic resistance of pathogenic bacteria. Chlorogenic acid (CA), as a kind of phenolic acid existing in many plants, has
Kun Chen, Chuantao Peng, Chuantao Peng, Fang Chi, Chundi Yu, Qingli Yang, Zhaojie Li, Zhaojie Li   +7 more
doaj   +1 more source

Padronização do ensaio pampa (Parallel Artificial Membrane Permeation Assay) e avaliação in vitro da permeabilidade intestinal e cutânea de compostos de origem natural e sintética [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Farmácia, Florianópolis, 2011O ensaio PAMPA tem demonstrado sua versatilidade desde 1998, sendo utilizado para avaliar a ...
Schneider, Naira Fernanda Zanchett
core