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Comprehensive Physiology, 2012
Abstract Cell migration is fundamental to establishing and maintaining the proper organization of multicellular organisms. Morphogenesis can be viewed as a consequence, in part, of cell locomotion, from large‐scale migrations of epithelial sheets during gastrulation, to the movement of individual cells during ...
Xavier, Trepat +2 more
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Abstract Cell migration is fundamental to establishing and maintaining the proper organization of multicellular organisms. Morphogenesis can be viewed as a consequence, in part, of cell locomotion, from large‐scale migrations of epithelial sheets during gastrulation, to the movement of individual cells during ...
Xavier, Trepat +2 more
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Biochemical Society Transactions, 2015
Human cells express 45 kinesins, microtubule motors that transport a variety of molecules and organelles within the cell. Many kinesins also modulate the tracks they move on by either bundling or sliding or regulating the dynamic assembly and disassembly of the microtubule polymer.
Alice, Bachmann, Anne, Straube
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Human cells express 45 kinesins, microtubule motors that transport a variety of molecules and organelles within the cell. Many kinesins also modulate the tracks they move on by either bundling or sliding or regulating the dynamic assembly and disassembly of the microtubule polymer.
Alice, Bachmann, Anne, Straube
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Seminars in Cell & Developmental Biology, 2015
Inhibitors of apoptosis (IAPs) constitute a family of cell signaling regulators controlling several fundamental biological processes such as innate immunity, inflammation, cell death, cell proliferation, and cell differentiation. Increasing evidence from in vivo and in vitro studies indicate a function for IAPs in the modulation of invasive and ...
Laurence, Dubrez, Krishnaraj, Rajalingam
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Inhibitors of apoptosis (IAPs) constitute a family of cell signaling regulators controlling several fundamental biological processes such as innate immunity, inflammation, cell death, cell proliferation, and cell differentiation. Increasing evidence from in vivo and in vitro studies indicate a function for IAPs in the modulation of invasive and ...
Laurence, Dubrez, Krishnaraj, Rajalingam
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Science, 1999
Cell movement is an elegant orchestration of different cellular processes that include microtubule dynamics, contraction of actin and myosin filaments, and the formation and turnover of integrin-rich adhesion complexes that serve as traction points over which the cell moves.
A R, Horwitz, J T, Parsons
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Cell movement is an elegant orchestration of different cellular processes that include microtubule dynamics, contraction of actin and myosin filaments, and the formation and turnover of integrin-rich adhesion complexes that serve as traction points over which the cell moves.
A R, Horwitz, J T, Parsons
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Current Opinion in Cell Biology, 1995
Adhesive interactions play a central role in cell migration. The regulation of these interactions requires the coordination of a multiplicity of signals, both spatially and temporally. The role of the integrin family has received considerable recent attention. Progress has been made in the elucidation of the mechanisms by which growth factors and other
A, Huttenlocher +2 more
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Adhesive interactions play a central role in cell migration. The regulation of these interactions requires the coordination of a multiplicity of signals, both spatially and temporally. The role of the integrin family has received considerable recent attention. Progress has been made in the elucidation of the mechanisms by which growth factors and other
A, Huttenlocher +2 more
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Microtubules in Cell Migration
Annual Review of Cell and Developmental Biology, 2013Migration is a polarized cellular process that opposes a protrusive front edge to a retracting trailing edge. From the front to the rear, actin-mediated forces sequentially promote cell protrusion, adhesion, contraction, and retraction. Over the past decade, microtubules have revealed their pivotal role in cell migration.
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Cell migration: Collective cell migration is intrinsically stressful
Current BiologyCollective cell migration is a key cellular process in development and disease. A new study reports that ER stress is induced during collective cell migration and an intrinsic mechanism prevents migratory cells from over-reacting to ER stress.
Heng, Wang, Jiong, Chen
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2011
Activins are the members of transforming growth factor β superfamily and act as secreted proteins; they were originally identified with a reproductive function, acting as endocrine-derived regulators of pituitary follicular stimulating hormone. In recent years, additional functions of activins have been discovered, including a regulatory role during ...
Hong-Yo, Kang, Chih-Rong, Shyr
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Activins are the members of transforming growth factor β superfamily and act as secreted proteins; they were originally identified with a reproductive function, acting as endocrine-derived regulators of pituitary follicular stimulating hormone. In recent years, additional functions of activins have been discovered, including a regulatory role during ...
Hong-Yo, Kang, Chih-Rong, Shyr
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Traffic, 2007
Most animal cells move cross‐linked surface antigens to one pole of the cell, a phenomenon called ‘capping’. It is closely related to the rearward movement of particles attached to their surface. Cap formation is one of the most accessible dynamic properties of cells and is closely related to how they move. Yet, how this occurs is unknown.
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Most animal cells move cross‐linked surface antigens to one pole of the cell, a phenomenon called ‘capping’. It is closely related to the rearward movement of particles attached to their surface. Cap formation is one of the most accessible dynamic properties of cells and is closely related to how they move. Yet, how this occurs is unknown.
openaire +2 more sources