Results 141 to 150 of about 8,672,364 (340)

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Zearalenone inhibits T cell chemotaxis by inhibiting cell adhesion and migration related proteins

Ecotoxicology and Environmental Safety, 2019
Zearalenone (ZEA) is a phenolic resorcylic acid lactone mycotoxin produced by several Fusarium species that grow on temperate and tropical crops. The number of reports documenting the immunotoxic effects of ZEA is increasing, but the underlying mechanism is not clear.
Guodong, Cai, Shunye, Pan, Nannan, Feng, Hui, Zou, Jianhong, Gu, Yan, Yuan, Xuezhong, Liu, Zongping, Liu, Jianchun, Bian   +8 more
openaire   +2 more sources

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Control of human endometrial stromal cell motility by PDGF-BB, HB-EGF and trophoblast-secreted factors [PDF]

, 2013
Human implantation involves extensive tissue remodeling at the fetal-maternal interface. It is becoming increasingly evident that not only trophoblast, but also decidualizing endometrial stromal cells are inherently motile and invasive, and likely ...
Annemarie Samalecos, Annemarie Samalecos (275635), Anja Wolf (275636), Weimar, C.H., Philipp Velicky, Michelle Kruse (275634), Wolf Anja, Kruse Michelle, Nick S Macklon, Macklon Nick S., Charlotte H. E. Weimar (148304), Nick S. Macklon (148320), Velicky Philipp, Weimar Charlotte H. E., Maren Schwenke, Philipp Velicky (275632), Gellersen Birgit, Schwenke, M., Maren Schwenke (275628), Knöfler Martin, Schwenke Maren, Gellersen, B., Samalecos Annemarie, Wolf, A., Bamberger, A.M., Martin Knöfler, Anja Wolf, Bamberger Ana-Maria, Michelle Kruse, Charlotte H E Weimar, Birgit Gellersen (148307), Velicky, P., Ana-Maria Bamberger, Ana-Maria Bamberger (275637), Kruse, M., Macklon, N.S., Birgit Gellersen, Knofler, M., Samalecos, A., Martin Knöfler (275630)   +39 more
core   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

The migration-security nexus. International migration and security before and after 9/11 [PDF]

, 2003
Faist T. The migration-security nexus. International migration and security before and after 9/11. COMCAD Arbeitspapiere - working papers, 9.
Thomas Faist, Faist, Thomas
core   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Lycopene treatment of prostate cancer cell lines inhibits adhesion and migration properties of the cells [PDF]

, 2014
licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited.
Cooper, Alan, Chopra, Mridula, Simone Elgass, Elgass, Simone, Mridula Chopra, Alan Cooper   +5 more
core   +1 more source

Candida and Porphyromonas gingivalis: the effect on wound closure in vitro

Journal of Oral Microbiology, 2017
Microorganisms play a role in oral mucositis after cancer therapy. The current study explored the hypothesis that Candida spp. alone and together with Porphyromonas gingivalis cause delayed healing of oral ulcerations due to the inhibition of wound ...
Thijs M. Haverman, Alexa M. G. A. Laheij, Johannes J. de Soet, Jan de Lange, Frederik R. Rozema   +4 more
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source