Results 11 to 20 of about 8,672,364 (340)
International Journal of Nanomedicine, 2018 Haobo Han,1,2 Wenqi Chen,2 Jiebing Yang,2 Xiao Liang,2 Yudi Wang,2 Quanshun Li,2 Yan Yang,2 Kun Li1 1School of Nursing, 2Key Laboratory for Molecular Enzymology and Engineering of Ministry of Education, School of Life Sciences, Jilin University ...
Han H +7 more
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A PDK1-dependent regulation of PLCγ1 activation is essential for cancer cell migration and invasion [PDF]
, 2011 PhDPhospholipase Cγ1 (PLCγ1) is highly expressed in several tumours such as breast carcinomas and has been found overexpressed in metastases compared to primary tumour in breast cancer patients, indicating that PLCγ1 may be important in tumourigenesis ...
Raimondi, Claudio
core +4 more sources
Ropivacaine inhibits proliferation, migration and invasion of human liver cancer cell line Hep3B [PDF]
Jichu yixue yu linchuang, 2022 Objective To study the effects of ropivacaine on the biological behaviour of liver cancer cell line Hep3B and to explore its molecular mechanism. Methods Hep3B cells were divided into the control group, ropivacaine group, si-NC group, si-LINC00853 group,
SUN Quan-peng, FAN Chao, ZHAN De-xi, FAN Yi-ming, SUN Wei-feng
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Journal of Nanobiotechnology, 2021 Background Approximately 80% of brain tumours are gliomas. Despite treatment, patient mortality remains high due to local metastasis and relapse. It has been shown that transferrin-functionalised porous silicon nanoparticles (Tf@pSiNPs) can inhibit the ...
Youssef Abdalla +5 more
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U1 snRNP regulates cancer cell migration and invasion in vitro
Nature Communications, 2020 Stimulated cells and cancer cells have widespread shortening of mRNA 3’-untranslated regions (3’UTRs) and switches to shorter mRNA isoforms due to usage of more proximal polyadenylation signals (PASs) in introns and last exons. U1 snRNP (U1), vertebrates’
Jung-Min Oh +10 more
semanticscholar +1 more source
IIp45 Inhibits Cell Migration through Inhibition of HDAC6 [PDF]
Journal of Biological Chemistry, 2010 IIp45 (aka MIIP) is a newly discovered gene whose protein product inhibits cell migration. HDAC6 is a class IIb deacetylase that specifically deacetylates alpha-tubulin, modulates microtubule dynamics, and promotes cell migration. A yeast two-hybrid assay using IIp45 as bait identified HDAC6 protein as a binding partner of IIp45.
Ying, Wu +5 more
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Upregulation of TCF21 inhibits migration of adrenocortical carcinoma cells [PDF]
Discover Oncology, 2021 Abstract Background Adrenocortical carcinomas (ACC) are rare and aggressive cancer. Our previous study has revealed that the transcription factor 21, TCF21, is downregulated in ACC and regulates steroidogenic factor 1 (SF-1) binding to the SF-1 E-box promoter.
Jean Lucas Kremer +3 more
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Computational and Structural Biotechnology Journal, 2020 Epithelial cells respond to their physical neighborhood with mechano-sensitive behaviors required for development and tissue maintenance. These include anchorage dependence, matrix stiffness-dependent proliferation, contact inhibition of proliferation ...
Eric Guberman +2 more
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bioRxiv, 2020 Only a fraction of cancer patients benefits from immune checkpoint inhibitors. This may be partly due to the dense extracellular matrix (ECM) that forms a barrier for T cells.
A. Nicolás-Boluda +15 more
semanticscholar +1 more source
Inhibition of cell migration by PITENINs: the role of ARF6 [PDF]
Oncogene, 2011 We have reported previously the development of small-molecule phosphatidylinositol-3,4,5-trisphosphate (PIP3) antagonists (PITs) that block pleckstrin homology (PH) domain interaction, including activation of Akt, and show anti-tumor potential. Here we show that the same molecules inhibit growth factor-induced actin remodeling, lamellipodia formation ...
Miao, Benchun +9 more
openaire +5 more sources