Integrative transcriptomic analysis in human and mouse model of anaphylaxis identifies gene signatures associated with cell movement, migration and neuroinflammatory signalling [PDF]
Frontiers in Immunology, 2022 BackgroundAnaphylaxis is an acute life-threatening allergic reaction and a concern at a global level; therefore, further progress in understanding the underlying mechanisms and more effective strategies for diagnosis, prevention and management are needed.
Matija Rijavec +14 more
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ATP levels influence cell movement during the mound phase in Dictyostelium discoideum as revealed by ATP visualization and simulation [PDF]
FEBS Open Bio, 2022 Cell migration plays an important role in multicellular organism development. The cellular slime mold Dictyostelium discoideum is a useful model organism for the study of cell migration during development.
Haruka Hiraoka +6 more
doaj +2 more sources
Tetraspanin CD82 interaction with cholesterol promotes extracellular vesicle–mediated release of ezrin to inhibit tumour cell movement [PDF]
Journal of Extracellular Vesicles, 2020 Tumour metastasis suppressor KAI1/CD82 inhibits tumour cell movement. As a transmembrane protein, tetraspanin CD82 bridges the interactions between membrane microdomains of lipid rafts and tetraspanin-enriched microdomains (TEMs). In this study, we found
Chao Huang +4 more
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The Forces Behind Cell Movement [PDF]
International Journal of Biological Sciences, 2007 Cell movement is a complex phenomenon primarily driven by the actin network beneath the cell membrane, and can be divided into three general components: protrusion of the leading edge of the cell, adhesion of the leading edge and deadhesion at the cell ...
Revathi Ananthakrishnan, Allen Ehrlicher
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Specificity of Plant Rhabdovirus Cell-to-Cell Movement. [PDF]
J Virol, 2019 Local transport of plant rhabdoviruses likely involves the passage of viral nucleocapsids through MP-gated plasmodesmata, but the molecular mechanisms are not fully understood. We have conducted complementation assays with MPs encoded by five distinct rhabdoviruses to assess their movement specificity.
Zhou X +6 more
europepmc +6 more sources
The use of animal models in rheumatoid arthritis research [PDF]
Journal of Yeungnam Medical Science, 2023 The pathological hallmark of rheumatoid arthritis (RA) is a synovial pannus that comprises proliferating and invasive fibroblast-like synoviocytes, infiltrating inflammatory cells, and an associated neoangiogenic response.
Jin-Sun Kong +2 more
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DBNLS232 regulates formation of filopodia and promotes cell migration in A549 cells
陆军军医大学学报, 2023 Objective To investigate the role of site-specific phosphorylation of adaptor protein Drebrin-like (DBNL) in regulating the formation of filopodia and the migration and movement of lung cancer A549 cells.
YIN Xun, YIN Xun, ZHANG Tao, ZHANG Tao
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Integrated analysis of cell shape and movement in moving frame
Biology Open, 2021 The cell's movement and morphological change are two interrelated cellular processes. An integrated analysis is needed to explore the relationship between them. However, it has been challenging to investigate them as a whole. The cell's trajectory can be
Yusri Dwi Heryanto +5 more
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Frontiers in Cell and Developmental Biology, 2021 Adhesion of basal keratinocytes to the underlying extracellular matrix (ECM) plays a key role in the control of skin homeostasis and response to injury.
Willow Hight-Warburton +8 more
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Transcriptional Changes in CD16+ Monocytes May Contribute to the Pathogenesis of COVID-19
Frontiers in Immunology, 2021 The COVID-19 pandemic has caused more than three million deaths globally. The severity of the disease is characterized, in part, by a dysregulated immune response.
Vanessa Chilunda +10 more
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