Statistical Modelling of Cell Movement [PDF]
In this paper we demonstrate an application of the unscented Kalman filter in the context of cell movement, using a model defined in terms of stochastic differential equations (SDEs)
Giurghita, Diana, Husmeier, Dirk
core +7 more sources
Integrative transcriptomic analysis in human and mouse model of anaphylaxis identifies gene signatures associated with cell movement, migration and neuroinflammatory signalling [PDF]
BackgroundAnaphylaxis is an acute life-threatening allergic reaction and a concern at a global level; therefore, further progress in understanding the underlying mechanisms and more effective strategies for diagnosis, prevention and management are needed.
Matija Rijavec+14 more
doaj +2 more sources
ATP levels influence cell movement during the mound phase in Dictyostelium discoideum as revealed by ATP visualization and simulation [PDF]
Cell migration plays an important role in multicellular organism development. The cellular slime mold Dictyostelium discoideum is a useful model organism for the study of cell migration during development.
Haruka Hiraoka+6 more
doaj +2 more sources
Tetraspanin CD82 interaction with cholesterol promotes extracellular vesicle–mediated release of ezrin to inhibit tumour cell movement [PDF]
Tumour metastasis suppressor KAI1/CD82 inhibits tumour cell movement. As a transmembrane protein, tetraspanin CD82 bridges the interactions between membrane microdomains of lipid rafts and tetraspanin-enriched microdomains (TEMs). In this study, we found
Chao Huang+4 more
doaj +2 more sources
Specificity of Plant Rhabdovirus Cell-to-Cell Movement. [PDF]
Local transport of plant rhabdoviruses likely involves the passage of viral nucleocapsids through MP-gated plasmodesmata, but the molecular mechanisms are not fully understood. We have conducted complementation assays with MPs encoded by five distinct rhabdoviruses to assess their movement specificity.
Zhou X+6 more
europepmc +7 more sources
The Forces Behind Cell Movement [PDF]
Cell movement is a complex phenomenon primarily driven by the actin network beneath the cell membrane, and can be divided into three general components: protrusion of the leading edge of the cell, adhesion of the leading edge and deadhesion at the cell ...
Revathi Ananthakrishnan, Allen Ehrlicher
doaj +3 more sources
DBNLS232 regulates formation of filopodia and promotes cell migration in A549 cells
Objective To investigate the role of site-specific phosphorylation of adaptor protein Drebrin-like (DBNL) in regulating the formation of filopodia and the migration and movement of lung cancer A549 cells.
YIN Xun, YIN Xun, ZHANG Tao, ZHANG Tao
doaj +1 more source
The use of animal models in rheumatoid arthritis research [PDF]
The pathological hallmark of rheumatoid arthritis (RA) is a synovial pannus that comprises proliferating and invasive fibroblast-like synoviocytes, infiltrating inflammatory cells, and an associated neoangiogenic response.
Jin-Sun Kong+2 more
doaj +1 more source
Transcriptional Changes in CD16+ Monocytes May Contribute to the Pathogenesis of COVID-19
The COVID-19 pandemic has caused more than three million deaths globally. The severity of the disease is characterized, in part, by a dysregulated immune response.
Vanessa Chilunda+10 more
doaj +1 more source
Stem or progenitor cell–based strategies to combat ischemic heart disease and myocardial infarction, whether autologous transplantation or stimulation of resident populations, not only require detailed insight into transdifferentiation potential and functional coupling, but the efficacy of this approach is underpinned by the need to induce appropriate ...
Smart, N, Riley, P
openaire +4 more sources