Results 151 to 160 of about 52,621 (199)
Some of the next articles are maybe not open access.
The nucleolus: the magician's hat for cell cycle tricks
Current Opinion in Cell Biology, 2000The nucleolus, for decades considered a ribosome factory and site for ribosomal RNA synthesis and processing, has recently acquired new fame. Analyses of proteins important for cell-cycle regulation have shown that this organelle is used to sequester proteins, thereby inhibiting their activity.
, Visintin, , Amon
openaire +3 more sources
The Nucleolus of the Apodan Sertoli Cell
Nature, 1948THE association of desoxyribose nucleic acid with the nucleolus has been reported in a number of different types of cells. Hyden1 in nerve cells, Davidson2 in the rat liver cell and Koller3 in tumour cells, find that particles or granules giving a positive Feulgen reaction occur on the periphery of the Feulgen-negative nucleolus.
openaire +2 more sources
Proteomic profiling of the human T-cell nucleolus
Molecular Immunology, 2011The nucleolus, site of ribosome biogenesis, is a dynamic subnuclear organelle involved in diverse cellular functions. The size, number and organisation of nucleoli are cell-specific and while it remains to be established, the nucleolar protein composition would be expected to reflect lineage-specific transcriptional regulation of rDNA genes and have ...
Mohamed Ali, Jarboui +4 more
openaire +2 more sources
Coiled bodies in the nucleolus of breast cancer cells
Journal of Cell Science, 1994ABSTRACT Coiled bodies are a special type of small round nuclear body, composed of coiled fibers and granules, especially prominent in the nucleoplasm of highly active cells (Brasch and Ochs (1992)Exp. Cell Res. 202, 211-223). Although no specific function has been assigned to coiled bodies, they contain spliceosome snRNAs and proteins ...
Robert L. Ochs +3 more
openaire +2 more sources
Nucleolus‐associated J chains in myeloma cells
Scandinavian Journal of Haematology, 1986Bone marrow aspirates from 10 patients with multiple myeloma (6 IgG myeloma, 3 IgA myeloma, 1 Bence Jones myeloma) were examined for nucleolus‐associated localization of J chains. On light microscopy using the PAP method, almost all or a significant number of myeloma cells exhibited intranuclear spots stained with anti‐J chains in 3 (IgG myeloma) out ...
T, Kanoh +5 more
openaire +2 more sources
Annular nucleolus in Leydig cells of mouse
Zeitschrift f�r Zellforschung und Mikroskopische Anatomie, 1973Many mature Leydig cells of adult mice contain annular nucleoli. In the cytoplasm of these cells, there is an abundance of agranular endoplasmic reticulum and its modifications, i.e. membranous whorls and double-walled tubules. By contrast, the cytoplasm of Leydig cells with compact nucleoli shows abundant free ribosomes and granular endoplasmic ...
openaire +2 more sources
Two Types of Ribonucleoprotein in the Nucleolus of Mammalian Cells
Nature, 1959NUCLEOLAR differentiation has been recognized since the time of Gustav Valentin. Agassiz1 referred to a body within the nucleolus of the turtle egg as the “Valentinian vesicle”. Montgomery2 and Heidenhain3 called this structure the nucleolinus. Recently, it has been suggested that the appearance of vesicular or solid nucleolini is due to the presence ...
R, LOVE, T P, BHARADWAJ
openaire +2 more sources
Distribution of U3 snRNA in the nucleolus of CHO cells
Biology of the Cell, 1985Localization of snRNA at the ultrastructural level was studied in the nucleolus of CHO cells by EM autoradiography. In conditions where snRNA U3 is the only RNA species labelled in the nucleolus, silver grains were largely found at the periphery, over the granular ribonucleoprotein component and the perinucleolar condensed chromatin; this enrichment ...
G, Lacoste-Royal, R, Simard
openaire +2 more sources
The structure and behavior of the nucleolus organizers in mammalian cells
Chromosoma, 1967The regularly occurring secondary constrictions on metaphase chromosomes of mammalian cells prove to be nucleolus organizers as expected. The expression of nucleolus organizers as secondary constrictions, however, varies from cell to cell and from tissue to tissue, including cultivation in vitro.
T C, Hsu, B R, Brinkley, F E, Arrighi
openaire +2 more sources
Connecting the nucleolus to the cell cycle and human disease
The FASEB Journal, 2014Long known as the center of ribosome synthesis, the nucleolus is connected to cell cycle regulation in more subtle ways. One is a surveillance system that reacts promptly when rRNA synthesis or processing is impaired, halting cell cycle progression.
Robert Y L, Tsai, Thoru, Pederson
openaire +2 more sources