Results 51 to 60 of about 23,513,766 (356)

Differences in lamina joint anatomy cause cultivar differences in leaf inclination angle of rice

open access: yesPlant Production Science, 2018
Leaf erectness is an important agronomic trait for improving canopy photosynthesis in rice. It is well known that leaf inclination angle (LIA) decreases after expansion during ripening.
Nan Su San   +5 more
doaj   +1 more source

Effect of insulin upon the cellular character of rat adipose tissue

open access: yesJournal of Lipid Research, 1972
The effect of insulin upon the lipid content, and the number and size of fat cells in the epididymal, retroperitoneal, and subcutaneous adipose tissue of a large number of rats were examined.
Lester B. Salans   +2 more
doaj   +1 more source

Sickle Cell Disease Is an Inherent Risk for Asthma in a Sibling Comparison Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Sickle cell disease (SCD) and asthma share a complex relationship. Although estimates vary, asthma prevalence in children with SCD is believed to be comparable to or higher than the general population. Determining whether SCD confers an increased risk for asthma remains challenging due to overlapping symptoms and the ...
Suhei C. Zuleta De Bernardis   +9 more
wiley   +1 more source

Cell-Type-Specific Quantification of a Scaffold-Based 3D Liver Co-Culture

open access: yesMethods and Protocols, 2019
In order to increase the metabolic activity of human hepatocytes and liver cancer cell lines, many approaches have been reported in recent years. The metabolic activity could be increased mainly by cultivating the cells in 3D systems or co-cultures (with
Marc Ruoß   +9 more
doaj   +1 more source

Pazopanib Combined With Vincristine and Irinotecan in Relapsed Wilms Tumor: Encouraging Outcomes in a Heavily Pretreated Pediatric Cohort

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background While Wilms tumor (WT) typically has a favorable prognosis, relapsed cases—especially those with high‐risk histology—remain therapeutically challenging after intensive frontline therapy. The combination of vincristine and irinotecan has demonstrated activity in pediatric solid tumors, and pazopanib, a multi‐targeted tyrosine kinase ...
Maria Debora De Pasquale   +6 more
wiley   +1 more source

DNA-DAPI Interaction-Based Method for Cell Proliferation Rate Evaluation in 3D Structures

open access: yesCurrent Issues in Molecular Biology, 2021
Effective cell number monitoring throughout the three-dimensional (3D) scaffold is a key factor in tissue engineering. There are many methods developed to evaluate cell number in 2D environments; however, they often encounter limitations in 3D. Therefore,
Egidijus Šimoliūnas   +5 more
doaj   +1 more source

Potential Early Risk Biomarkers for Reduced Forced Expiratory Volume in Children Post‐Hematopoietic Cell Transplantation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT We sought to identify potential early risk biomarkers for lung disease in children post‐allogeneic HCT. Patients with pulmonary function tests 3 months post‐transplant and plasma samples between days 7 and 14 post‐HCT were included. Six of 27 subjects enrolled had reduced forced expiratory volume 1 (FEV1) z scores.
Isabella S. Small   +3 more
wiley   +1 more source

Personalizing the Pediatric Hematology/Oncology Fellowship: Adapting Training for the Next Generation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT The pediatric hematology‐oncology fellowship training curriculum has not substantially changed since its inception. The first year of training is clinically focused, and the second and third years are devoted to scholarship. However, this current structure leaves many fellows less competitive in the current job market, resulting in ...
Scott C. Borinstein   +3 more
wiley   +1 more source

Normalization and variance stabilization of single-cell RNA-seq data using regularized negative binomial regression

open access: yesGenome Biology, 2019
Single-cell RNA-seq (scRNA-seq) data exhibits significant cell-to-cell variation due to technical factors, including the number of molecules detected in each cell, which can confound biological heterogeneity with technical effects.
Christoph Hafemeister, R. Satija
semanticscholar   +1 more source

Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The combination of disease manifestations, the familial burden, and varying penetrance of endocrine tumor syndromes (ETSs) is unique. This review aimed to portray and summarize available data on psychosocial outcomes in patients with ETSs and explore gaps and opportunities for future research and care.
Daniël Zwerus   +6 more
wiley   +1 more source

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