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dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Hyperaminoacidemia from interrupted glucagon signaling increases pancreatic acinar cell proliferation and size via mTORC1 and YAP pathways

open access: gold
Chunhua Dai   +19 more
openalex   +1 more source

Extracellular vesicles released from Marek's disease virus-transformed T-cells impact immune cell proliferation. [PDF]

open access: yesJ Gen Virol
Trapp-Fragnet L   +5 more
europepmc   +1 more source

Impaired intestinal cell proliferation parallels increased senescence after burn injury in aged mice. [PDF]

open access: yesAm J Physiol Gastrointest Liver Physiol
Walrath TM   +7 more
europepmc   +1 more source
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Cell Proliferation

2013
Cellular proliferation, as a result of cell growth and cell division, is one of the most fundamental biological processes. Although there is a great deal which remains unclear, significant advances have been made in past decades in our understanding of the process and regulation of cell proliferation.
Zeng, Xiangqiong, Zhang, Changhong
openaire   +3 more sources

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