Results 91 to 100 of about 809,436 (268)

Hormone correction of dysfunctional metabolic gene expression in stem cell-derived liver tissue

Stem Cell Research & Therapy
The increase in metabolic dysfunction-associated steatotic liver disease (MASLD) and its progression to metabolic dysfunction-associated steatohepatitis (MASH) is a worldwide healthcare challenge. Heterogeneity between men and women in the prevalence and
Alvile Kasarinaite, Maria Jimenez Ramos, Mariana Beltran-Sierra, Elena F. Sutherland, Pedro Arede Rei, Make Zhao, Ying Chi, Meryam Beniazza, Andrea Corsinotti, Timothy J. Kendall, Neil C. Henderson, Jonathan A. Fallowfield, Philippa T. K. Saunders, David C. Hay   +13 more
doaj   +1 more source

Pulsed Electromagnetic Fields Induce Skeletal Muscle Cell Repair by Sustaining the Expression of Proteins Involved in the Response to Cellular Damage and Oxidative Stress. [PDF]

Int J Mol Sci, 2023
Maiullari S, Cicirelli A, Picerno A, Giannuzzi F, Gesualdo L, Notarnicola A, Sallustio F, Moretti B.   +7 more
europepmc   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Regenerative Scalp Preparation With Stromal Vascular Fraction and Platelet‐Rich Fibrin Prior to Hair Transplantation in Lichen Planus: A Case Report

Clinical Case Reports
Lichen planus (LP) is a chronic inflammatory scalp disorder that can lead to cicatricial alopecia, making it challenging for hair transplantation. This case report describes a 26‐year‐old female with LP who underwent scalp preparation using SVF and PRF ...
Pantea Bozorg Savoji, Seyedeh Nasim Mirbahari, Shohreh Rafiee, Tannaz Fakhim, Mohammad Ali Nilforoushzadeh   +4 more
doaj   +1 more source

Diminished schwann cell repair responses play a role in delayed diabetes-associated wound healing. [PDF]

Front Physiol, 2022
Zhou S, Wan L, Liu X, Hu D, Lu F, Chen X, Liang F.   +6 more
europepmc   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

AICAR attenuates postoperative abdominal adhesion formation by inhibiting oxidative stress and promoting mesothelial cell repair. [PDF]

PLoS One, 2022
Wu Y, Duan X, Gao Z, Yang N, Xue F.
europepmc   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

A Novel Treatment Schedule Combining Injectable Platelet‐Rich Fibrin and Endolift Laser for Facial Rejuvenation: A Case Report

Clinical Case Reports
The combination of Endolift laser therapy and injectable platelet‐rich fibrin (i‐PRF) is an emerging strategy in aesthetic medicine, but the optimal scheduling of these modalities remains unexplored. This case report highlights a novel treatment schedule
Mohammad Ali Nilforoushzadeh, Pantea Bozorg Savoji, Tannaz Fakhim, Seyedeh Nasim Mirbahari   +3 more
doaj   +1 more source