Results 11 to 20 of about 1,443,234 (190)
Microvesicles as vehicles for tissue regeneration: Changing of the guards [PDF]
, 2016 Purpose of Review: Microvesicles (MVs) have been recognised as mediators of stem cell function, enabling and guiding their regenerative effects. Recent Findings: MVs constitute one unique size class of extracellular vesicles (EVs) directly shed from ...
Davies, R. Wayne +3 more
core +1 more source
NMDAR mediated translation at the synapse is regulated by MOV10 and FMRP
Molecular Brain, 2019 Protein synthesis is crucial for maintaining synaptic plasticity and synaptic signalling. Here we have attempted to understand the role of RNA binding proteins, Fragile X Mental Retardation Protein (FMRP) and Moloney Leukemia Virus 10 (MOV10) protein in ...
Preeti Madhav Kute +4 more
doaj +1 more source
RAD6-RAD18-RAD5-pathway-dependent tolerance to chronic low-dose ultraviolet light [PDF]
, 2009 In nature, organisms are exposed to chronic low- dose ultraviolet light ( CLUV) as opposed to the acute high doses common to laboratory experiments. Analysis of the cellular response to acute high-dose exposure has delineated the importance of direct DNA
Carr, Antony M +3 more
core +1 more source
Scientific Reports, 2022 Recent research on normal human tissues identified omnipresent clones of cells, driven by somatic mutations known to be responsible for carcinogenesis (e.g., in TP53 or NOTCH1). These new insights are fundamentally changing current tumor evolution models,
Tom Luijts +10 more
doaj +1 more source
Stem cells for myocardial repair [PDF]
Thrombosis and Haemostasis, 2010 SummaryThere is a growing interest in the clinical application for stem cell as a novel therapy for treatment of acute myocardial infarction and chronic myocardial ischaemia. The initial premise is the transplanted exogenous stem cells can engraft and integrate with host myocardium for cardiac regeneration.
Liu, Y +4 more
openaire +4 more sources
Only complete rejoining of DNA strand breaks after UVC allows K562 cell proliferation and DMSO induction of erythropoiesis [PDF]
, 2008 DNA strand breaks are early intermediates of the repair of UVC-induced DNA damage, however, since they severely impair cellular activities, their presence should be limited in time.
AVALLONE, BICE, FORESTI, MAGDA
core +1 more source
NEDD4-1 deficiency impairs satellite cell function during skeletal muscle regeneration
Biological Research, 2023 Background Satellite cells are tissue-specific stem cells primarily responsible for the regenerative capacity of skeletal muscle. Satellite cell function and maintenance are regulated by extrinsic and intrinsic mechanisms, including the ubiquitin ...
Felipe Cabezas +6 more
doaj +1 more source
Cell aging preserves cellular immortality in the presence of lethal levels of damage. [PDF]
, 2019 Cellular aging, a progressive functional decline driven by damage accumulation, often culminates in the mortality of a cell lineage. Certain lineages, however, are able to sustain long-lasting immortality, as prominently exemplified by stem cells.
Chao, Lin +4 more
core +3 more sources
Utilizing osteocyte derived factors to enhance cell viability and osteogenic matrix deposition within IPN hydrogels [PDF]
, 2020 Many bone defects arising due to traumatic injury, disease, or surgery are unable to regenerate, requiring intervention. More than four million graft procedures are performed each year to treat these defects making bone the second most commonly ...
Hoey, David A. +2 more
core +1 more source
Scientific Reports, 2023 Age-related macular degeneration (AMD) is a complex disease caused by different genetic and environmental risk factors leading to loss of cells in the central part of the retina.
Almar Neiteler +3 more
doaj +1 more source