Results 21 to 30 of about 809,436 (268)

Transplantation of GABAergic Cells Derived from Bioreactor-Expanded Human Neural Precursor Cells Restores Motor and Cognitive Behavioral Deficits in a Rodent Model of Huntington's Disease

Cell Transplantation, 2013
Huntington's disease (HD) is a neurodegenerative disorder that is characterized by progressive dementia, choreiform involuntary movements, and emotional deterioration.
Marcus C. McLeod, Nao R. Kobayashi, Arindom Sen, Behnam A. Baghbaderani, Damaso Sadi, Ruperto Ulalia, Leo A. Behie, Ivar Mendez M.D., Ph.D.   +7 more
doaj   +1 more source

BDNF Induced Translation of Limk1 in Developing Neurons Regulates Dendrite Growth by Fine-Tuning Cofilin1 Activity

Frontiers in Molecular Neuroscience, 2019
Dendritic growth and branching are highly regulated processes and are essential for establishing proper neuronal connectivity. There is a critical phase of early dendrite development when these are heavily regulated by external cues such as trophic ...
Sreenath Ravindran, Sreenath Ravindran, Vijayalaxmi C. Nalavadi, Ravi S. Muddashetty   +3 more
doaj   +1 more source

Regulatory Effects of Damaged Renal Epithelial Cells After Repair by Porphyra yezoensis Polysaccharides with Different Sulfation Degree on the Calcium Oxalate Crystal–Cell Interaction

International Journal of Nanomedicine, 2021
Xin-Yuan Sun,1,* Hui Zhang,2,* Ji-Wang Deng,1,* Bang-Xian Yu,1 Yi-Han Zhang,1 Jian-Ming Ouyang2 1Department of Urology, Guangzhou Institute of Urology, Guangdong Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical ...
Sun XY, Zhang H, Deng JW, Yu BX, Zhang YH, Ouyang JM   +5 more
doaj  

Immunometabolism of pro-repair cells [PDF]

Journal of Clinical Investigation, 2019
Immune cell populations determine the balance between ongoing damage and repair following tissue injury. Cells responding to a tissue-damaged environment have significant bioenergetic and biosynthetic needs. In addition to supporting these needs, metabolic pathways govern the function of pro-repair immune cells, including regulatory T cells and tissue ...
Benjamin D. Singer, Navdeep S. Chandel
openaire   +2 more sources

Proteomics analysis of soluble secreted proteins of Lutzomyia longipalpis LL5 cells transfected with a dsRNA viral mimic: insights into cellular defense and repair signals

Frontiers in Cellular and Infection Microbiology
Sand flies, which transmit diseases like leishmaniases, bartonellosis, and certain viruses, pose a significant public health threat. Our research focuses on the immune responses of Lutzomyia longipalpis, the primary vector for visceral leishmaniasis in ...
Andrea Martins da Silva, Ilya Violeta Llanos Salamanca, Michel Batista, Michel Batista, Fabricio Klerynton Marchini, Fabricio Klerynton Marchini, Antonio Jorge Tempone, Erich Loza Telleria, Yara Maria Traub-Csekö   +8 more
doaj   +1 more source

Comparison of the adhesion and endocytosis of calcium oxalate dihydrate to HK-2 cells before and after repair by Astragalus polysaccharide

Science and Technology of Advanced Materials, 2019
This work investigated the effects of repairing injured renal proximal tubular epithelial (HK-2) cells by using three Astragalus polysaccharides (APS) with different molecular weights and the adhesion and endocytosis of HK-2 cells to the calcium oxalate ...
Jin Han, Da Guo, Xin-Yuan Sun, Jian-Min Wang, Jian-Ming Ouyang, Bao-Song Gui   +5 more
doaj   +1 more source

The Role of Dynamic miRISC During Neuronal Development

Frontiers in Molecular Biosciences, 2020
Activity-dependent protein synthesis plays an important role during neuronal development by fine-tuning the formation and function of neuronal circuits.
Bharti Nawalpuri, Bharti Nawalpuri, Sreenath Ravindran, Sreenath Ravindran, Ravi S. Muddashetty   +4 more
doaj   +1 more source

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar, Karen Thibaudeau, Mary Mathias, Heather McDaniel, Madlen Reschke, Klaus Tenbrock, Joseph M. Parker, Amy Shapiro   +7 more
wiley   +1 more source

The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo, Miriam A. Bornhorst, Angela J. Waanders, Sara Zarnegar‐Lumley, Ashwin Lakshman Koppayi, Lucy A. Godley   +5 more
wiley   +1 more source

Procesos puntuales, densidades producto y biología celular

Revista Colombiana de Estadística, 2005
En este artículo se explica cómo los procesos puntuales han sido usados con éxito para modelar problemas de poblaciones celulares. En particular, se muestra la utilidad de la técnica de densidades producto para tratar un problema de células sujetas a ...
VISWANATHAN ARUNACHALAM
doaj   +2 more sources