Results 21 to 30 of about 13,519,306 (307)
Stem cells for myocardial repair [PDF]
SummaryThere is a growing interest in the clinical application for stem cell as a novel therapy for treatment of acute myocardial infarction and chronic myocardial ischaemia. The initial premise is the transplanted exogenous stem cells can engraft and integrate with host myocardium for cardiac regeneration.
Liu, Y +4 more
openaire +4 more sources
NEDD4-1 deficiency impairs satellite cell function during skeletal muscle regeneration
Background Satellite cells are tissue-specific stem cells primarily responsible for the regenerative capacity of skeletal muscle. Satellite cell function and maintenance are regulated by extrinsic and intrinsic mechanisms, including the ubiquitin ...
Felipe Cabezas +6 more
doaj +1 more source
Age-related macular degeneration (AMD) is a complex disease caused by different genetic and environmental risk factors leading to loss of cells in the central part of the retina.
Almar Neiteler +3 more
doaj +1 more source
The remarkable feature of Schwann cells (SCs) to transform into a repair phenotype turned the spotlight on this powerful cell type. SCs provide the regenerative environment for axonal re‐growth after peripheral nerve injury (PNI) and play a vital role in
T. Weiss +12 more
semanticscholar +1 more source
c-Abl Kinase Is Required for Satellite Cell Function Through Pax7 Regulation
Satellite cells (SCs) are tissue-specific stem cells responsible for adult skeletal muscle regeneration and maintenance. SCs function is critically dependent on two families of transcription factors: the paired box (Pax) involved in specification and ...
Fabián Montecino +6 more
doaj +1 more source
Mesenchymal Stem Cell Migration and Tissue Repair
Mesenchymal stem cells (MSCs) are multilineage cells with the ability to self-renew and differentiate into a variety of cell types, which play key roles in tissue healing and regenerative medicine.
Xiaorong Fu +5 more
semanticscholar +1 more source
Heart repair and stem cells [PDF]
Of the medical conditions currently being discussed in the context of possible treatments based on cell transplantation therapy, few have received more attention than the heart. Much focus has been on the potential application of bone marrow‐derived cell preparations, which have already been introduced into double‐blind, placebo‐controlled clinical ...
Linda W, van Laake +3 more
openaire +2 more sources
Bone repair and stem cells [PDF]
Bones are an important component of vertebrates; they grow explosively in early life and maintain their strength throughout life. Bones also possess amazing capabilities to repair-the bone is like new without a scar after complete repair. In recent years, a substantial progress has been made in our understanding on mammalian bone stem cells.
Noriaki, Ono, Henry M, Kronenberg
openaire +2 more sources
Transplantation of Bioreactor-Produced Neural Stem Cells into the Rodent Brain
The development of new cell replacement strategies using neural stem cells (NSC) may provide an alternative and unlimited cell source for clinical neural transplantation in neurodegenerative diseases such as Parkinson's and Huntington's disease.
M. Mcleod Ph.D. +6 more
doaj +1 more source
A 3D Cell Death Assay to Quantitatively Determine Ferroptosis in Spheroids
The failure of drug efficacy in clinical trials remains a big issue in cancer research. This is largely due to the limitations of two-dimensional (2D) cell cultures, the most used tool in drug screening.
Robin Demuynck +4 more
doaj +1 more source

