Results 31 to 40 of about 1,443,234 (190)
Cell aging and kidney repair [PDF]
Acute kidney injury (AKI), a rapid loss of renal function, is a major clinical problem associated with a high degree of morbidity and mortality. During AKI, a stressor, such as ischemia-reperfusion (IR), causes tubular cell death, interstitial inflammation and vascular damage.
Nathan, Susnik +2 more
openaire +2 more sources
The p53-MDM2 network: from oscillations to apoptosis [PDF]
The p53 protein is well-known for its tumour suppressor function. The p53-MDM2 negative feedback loop constitutes the core module of a network of regulatory interactions activated under cellular stress.
Bose, Indrani, Ghosh, Bhaswar
core +2 more sources
Cell therapy for cardiac repair [PDF]
Heart failure is a leading cause of morbidity and mortality worldwide. The current strategies for treatment are limited and new therapeutic approaches are needed. This review describes research performed in animal models of cardiac disease and clinical trials and discusses the mechanisms involved in possible beneficial effects of cell therapy.
Joon, Lee, Cesare M, Terracciano
openaire +2 more sources
The cell cycle–apoptosis connection revisited in the adult brain [PDF]
Adult neurogenesis is studied in vivo using thymidine analogues such as bromodeoxyuridine (BrdU) to label DNA synthesis during the S phase of the cell cycle.
Bauer, Sylvian, Patterson, Paul H.
core +3 more sources
Huntington's disease (HD) is a neurodegenerative disorder that is characterized by progressive dementia, choreiform involuntary movements, and emotional deterioration.
Marcus C. McLeod +7 more
doaj +1 more source
Dendritic growth and branching are highly regulated processes and are essential for establishing proper neuronal connectivity. There is a critical phase of early dendrite development when these are heavily regulated by external cues such as trophic ...
Sreenath Ravindran +3 more
doaj +1 more source
Stem Cell Differentiation: Cardiac Repair [PDF]
Cellular transplantation has been employed for several years to deliver donor cardiomyocytes to normal and injured hearts. Recent reports of a variety of stem cells with apparent cardiomyogenic potential have raised the possibility of cell transplantation-based therapeutic interventions for heart disease.
Michael, Rubart, Loren J, Field
openaire +2 more sources
Prostaglandin E2 promotes intestinal repair through an adaptive cellular response of the epithelium [PDF]
Adaptive cellular responses are often required during wound repair. Following disruption of the intestinal epithelium, wound‐associated epithelial (WAE) cells form the initial barrier over the wound.
Lai, Chin-Wen +7 more
core +2 more sources
Elevated expression of artemis in human fibroblast cells is associated with cellular radiosensitivity and increased apoptosis [PDF]
Copyright @ 2012 Nature Publishing GroupThis article has been made available through the Brunel Open Access Publishing Fund.Background: The objective of this study was to determine the molecular mechanism(s) responsible for cellular radiosensitivity in ...
A Musio +30 more
core +1 more source
Xin-Yuan Sun,1,* Hui Zhang,2,* Ji-Wang Deng,1,* Bang-Xian Yu,1 Yi-Han Zhang,1 Jian-Ming Ouyang2 1Department of Urology, Guangzhou Institute of Urology, Guangdong Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical ...
Sun XY +5 more
doaj

