Results 31 to 40 of about 1,443,234 (190)

Cell aging and kidney repair [PDF]

open access: yesCell Cycle, 2015
Acute kidney injury (AKI), a rapid loss of renal function, is a major clinical problem associated with a high degree of morbidity and mortality. During AKI, a stressor, such as ischemia-reperfusion (IR), causes tubular cell death, interstitial inflammation and vascular damage.
Nathan, Susnik   +2 more
openaire   +2 more sources

The p53-MDM2 network: from oscillations to apoptosis [PDF]

open access: yes, 2007
The p53 protein is well-known for its tumour suppressor function. The p53-MDM2 negative feedback loop constitutes the core module of a network of regulatory interactions activated under cellular stress.
Bose, Indrani, Ghosh, Bhaswar
core   +2 more sources

Cell therapy for cardiac repair [PDF]

open access: yesBritish Medical Bulletin, 2010
Heart failure is a leading cause of morbidity and mortality worldwide. The current strategies for treatment are limited and new therapeutic approaches are needed. This review describes research performed in animal models of cardiac disease and clinical trials and discusses the mechanisms involved in possible beneficial effects of cell therapy.
Joon, Lee, Cesare M, Terracciano
openaire   +2 more sources

The cell cycle–apoptosis connection revisited in the adult brain [PDF]

open access: yes, 2005
Adult neurogenesis is studied in vivo using thymidine analogues such as bromodeoxyuridine (BrdU) to label DNA synthesis during the S phase of the cell cycle.
Bauer, Sylvian, Patterson, Paul H.
core   +3 more sources

Transplantation of GABAergic Cells Derived from Bioreactor-Expanded Human Neural Precursor Cells Restores Motor and Cognitive Behavioral Deficits in a Rodent Model of Huntington's Disease

open access: yesCell Transplantation, 2013
Huntington's disease (HD) is a neurodegenerative disorder that is characterized by progressive dementia, choreiform involuntary movements, and emotional deterioration.
Marcus C. McLeod   +7 more
doaj   +1 more source

BDNF Induced Translation of Limk1 in Developing Neurons Regulates Dendrite Growth by Fine-Tuning Cofilin1 Activity

open access: yesFrontiers in Molecular Neuroscience, 2019
Dendritic growth and branching are highly regulated processes and are essential for establishing proper neuronal connectivity. There is a critical phase of early dendrite development when these are heavily regulated by external cues such as trophic ...
Sreenath Ravindran   +3 more
doaj   +1 more source

Stem Cell Differentiation: Cardiac Repair [PDF]

open access: yesCells Tissues Organs, 2007
Cellular transplantation has been employed for several years to deliver donor cardiomyocytes to normal and injured hearts. Recent reports of a variety of stem cells with apparent cardiomyogenic potential have raised the possibility of cell transplantation-based therapeutic interventions for heart disease.
Michael, Rubart, Loren J, Field
openaire   +2 more sources

Prostaglandin E2 promotes intestinal repair through an adaptive cellular response of the epithelium [PDF]

open access: yes, 2017
Adaptive cellular responses are often required during wound repair. Following disruption of the intestinal epithelium, wound‐associated epithelial (WAE) cells form the initial barrier over the wound.
Lai, Chin-Wen   +7 more
core   +2 more sources

Elevated expression of artemis in human fibroblast cells is associated with cellular radiosensitivity and increased apoptosis [PDF]

open access: yes, 2012
Copyright @ 2012 Nature Publishing GroupThis article has been made available through the Brunel Open Access Publishing Fund.Background: The objective of this study was to determine the molecular mechanism(s) responsible for cellular radiosensitivity in ...
A Musio   +30 more
core   +1 more source

Regulatory Effects of Damaged Renal Epithelial Cells After Repair by Porphyra yezoensis Polysaccharides with Different Sulfation Degree on the Calcium Oxalate Crystal–Cell Interaction

open access: yesInternational Journal of Nanomedicine, 2021
Xin-Yuan Sun,1,* Hui Zhang,2,* Ji-Wang Deng,1,* Bang-Xian Yu,1 Yi-Han Zhang,1 Jian-Ming Ouyang2 1Department of Urology, Guangzhou Institute of Urology, Guangdong Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical ...
Sun XY   +5 more
doaj  

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