Results 121 to 130 of about 12,492,811 (359)

Loss of CHT3 in Candida albicans wild-type strains increases surface-exposed chitin and affects host-pathogen interaction

Frontiers in Cellular and Infection Microbiology
The chitinase Cht3 plays a major role in the chitinolytic activity of the pathogenic yeast Candida albicans and has also been proposed as a major antigen with potential for vaccine development against systemic candidiasis.
María Teresa Blázquez-Muñoz, Augusto Costa-Barbosa, Augusto Costa-Barbosa, María Alvarado, Alexandre Mendonça, Alexandre Mendonça, Sami Benkhellat, Sami Benkhellat, Manuel Vilanova, Manuel Vilanova, Manuel Vilanova, Sebastián Fernández-Sánchez, Alexandra Correia, Alexandra Correia, Alexandra Correia, Piet W. J. de Groot, Paula Sampaio, Paula Sampaio   +17 more
doaj   +1 more source

Immunomagnetic bead separation of mononuclear cells from contaminating granulocytes in cryopreserved blood samples

, 2009
Sergey N. Preobrazhensky, David W. Bahler   +1 more
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

FtsEX-independent control of RipA-mediated cell separation in Corynebacteriales. [PDF]

Proc Natl Acad Sci U S A, 2022
Gaday Q, Megrian D, Carloni G, Martinez M, Sokolova B, Ben Assaya M, Legrand P, Brûlé S, Haouz A, Wehenkel AM, Alzari PM.   +10 more
europepmc   +1 more source

Establishment of a simple separation process for highly pure .BETA.-carotene from cultured carrot cells.

, 1991
Katsuya Ogawa, Taku Matsushita, Kazumori Funatsu   +2 more
openalex   +2 more sources

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Recent advances in microfluidic cell separation to enable centrifugation-free, low extracorporeal volume leukapheresis in pediatric patients. [PDF]

Blood Transfus, 2023
Iqbal M, Mukhamedshin A, Lezzar DL, Abhishek K, McLennan AL, Lam FW, Shevkoplyas SS.   +6 more
europepmc   +1 more source

Computational Models for Optimizing Particle Separation in Spiral Inertial Microfluidics: A Step Toward Enhanced Biosensing and Cell Sorting [PDF]

Julian Tristan Joshua Boland, Zhenxu Yang, Qiankun Yin, Xiaochen Liu, Zhejun Xu, Kien Voon Kong, Daniele Vigolo, Ken‐Tye Yong   +7 more
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

TOR complex 1 negatively regulates NDR kinase Cbk1 to control cell separation in budding yeast. [PDF]

PLoS Biol, 2023
Foltman M, Mendez I, Bech-Serra JJ, de la Torre C, Brace JL, Weiss EL, Lucas M, Queralt E, Sanchez-Diaz A.   +8 more
europepmc   +1 more source