TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
Latent DNA of Epstein-Barr Virus: Separation from High-Molecular-Weight Cell DNA in a Neutral Glycerol Gradient [PDF]
, 1974 Akiko Tanaka, Meihan Nonoyama
openalex +1 more source
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
Optimal Parameter Configuration of a Microfluidic Chip for High-Throughput, Label-Free Circulating Tumor Cell Separation and Enrichment Based on Inertial Focusing. [PDF]
Diagnostics (Basel), 2023 Sun X +6 more
europepmc +1 more source
Antibody enhancement of free-flow electrophoresis [PDF]
Specific T cell clones and antibodies (ABs) were developed to study the efficiency of purifying closely associated T cells using Continuous Flow Electrophoresis System.
Atassi, M. Zouhair +2 more
core +1 more source
Teichoic acids: antigenic determinants, chain separation, and their location in the cell wall.
, 1966 Max M. Burger
openalex +1 more source
Cell Wall‐Bridge Maintaining Three Dimensional Structure of Cell Packets Formed by the Localized Suppression of Cell Separation of a Micrococcus lysodeikticus (luteus) Mutant1 [PDF]
, 1979 Toshihiko Monodane +2 more
openalex +1 more source
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
Recent Developments in Inertial and Centrifugal Microfluidic Systems along with the Involved Forces for Cancer Cell Separation: A Review. [PDF]
Sensors (Basel), 2023 Farahinia A, Zhang W, Badea I.
europepmc +1 more source
THE SEPARATION OF DIFFERENT CELL CLASSES FROM LYMPHOID ORGANS [PDF]
, 1971 Ken Shortman +5 more
openalex +1 more source