Results 71 to 80 of about 1,800,217 (375)
FEBS Letters, EarlyView.Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke +2 more
wiley +1 more source
Current Directions in Biomedical Engineering, 2020 Within the human blood immune cells assume specific functions to modulate and control the human immune response. Consequently, they are used for the diagnosis and treatment of autoimmune and hematologic diseases.
Behrens Stephan +2 more
doaj +1 more source
Micromachines, 2020 Separation of circulating tumor cells (CTCs) from blood samples and subsequent DNA extraction from these cells play a crucial role in cancer research and drug discovery.
Rohollah Nasiri +5 more
doaj +1 more source
Clustering and ordering in cell assemblies with generic asymmetric aligning interactions [PDF]
arXiv, 2020 Collective cell migration plays an essential role in various biological processes, such as development or cancer proliferation. While cell-cell interactions are clearly key determinants of collective cell migration -- in addition to individual cells self-propulsion -- the physical mechanisms that control the emergence of cell clustering and collective ...
arxiv
Velde: constructing cell potential landscapes by RNA velocity vector field decomposition [PDF]
arXiv, 2023 The Waddington landscape serves as a metaphor illustrating the developmental process of cells, likening it to a small ball rolling down various trajectories into valleys. Constructing an epigenetic landscape of this nature aids in visualizing and gaining insights into cell differentiation. Development encompasses intricate processes involving both cell
arxiv
Differences in mechanical properties lead to anomalous phase separation in a model cell co-culture [PDF]
Soft Matter (2021), 2019 During the morphogenesis of tissues and tumors, cells often interact with neighbors with different mechanical properties, but the understanding of its role is lacking. We use active Brownian Dynamics simulations to study a model co-culture consisting of two types of cells with the same size and self-propulsion speed, but different mechanical stiffness ...
arxiv +1 more source
, 2021 Many processors are available for separating particles and/or cells, but few can match the capacity of flow cytometry – in particular the sorting component. Several aspects unique to cell sorting give it such power. First, particles can be separated based on size, complexity, fluorescence, or any combination of these parameters.
openaire +4 more sources
Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis
FEBS Letters, EarlyView.Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner +7 more
wiley +1 more source
Numerical Simulation of a Lab-on-Chip for Dielectrophoretic Separation of Circulating Tumor Cells
Micromachines, 2023 Circulating tumor cells (CTCs) are cancer cells detached from tumors that enter the bloodstream with the rest of the blood cells before settling on remote organs and growing. CTCs play a major role as a target for cancer diagnosis.
Abdallah M. Alkhaiyat, Mohamed Badran
doaj +1 more source
Analytical and numerical stability analysis of Soret-driven convection in a horizontal porous layer [PDF]
, 2007 We present an analytical and numerical stability analysis of Soret-driven convection in a porous cavity saturated by a binary fluid. Both the mechanical equilibrium solution and the monocellular flow obtained for particular ranges of the physical ...
A. Mojtabi +7 more
core +1 more source