Results 111 to 120 of about 14,296,855 (364)
Quorum sensing mediates morphology and motility transitions in the model archaeon Haloferax volcanii
mBioQuorum sensing (QS) is a population density-dependent mechanism of intercellular communication, whereby microbes secrete and detect signals to regulate behaviors such as virulence and biofilm formation.
Priyanka Chatterjee +6 more
doaj +1 more source
Cell Form and Function: Interpreting and Controlling the Shape of Adherent Cells.
Trends in Biotechnology, 2019 Beautiful images of animal cells cultured on surfaces are ubiquitous in biological research, but these shapes also carry valuable information about the cells and the organism that they came from.
A. Prasad, Elaheh Alizadeh
semanticscholar +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Cells: shaping tissues and organs
Molecular Biology of the Cell, 2014 mbc.E13-11-0670 Molecular Biology of the Cell Volume 25 Page 730 MBoC is pleased to publish this summary of the Minisymposium “Cells Shaping Tissues: Mechanisms Underlying Cell Polarity, Fate Specification, and Morphogenesis” held at the American Society for Cell Biology 2013 Annual Meeting, New Orleans, LA, December 15, 2013.
Gartner, Zev, Rosenblatt, J
openaire +4 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Single-Cell RNA Sequencing in Lung Cancer: Revealing Phenotype Shaping of Stromal Cells in the Microenvironment [PDF]
, 2022 Jianhong Zhang +3 more
openalex +1 more source
Shaping the T cell repertoire. [PDF]
The Journal of Immunology, 2005 Today immunologists are well aware of positive and negative selection of developing T cells. This was very different almost three decades ago when MHC-restricted Ag recognition by T cells represented an enormous puzzle in the absence of data on the molecular nature of Ag recognition by T cells ...
openaire +5 more sources