Results 101 to 110 of about 890,746 (314)
Getting Cells and Tissues into Shape [PDF]
Cell, 2011 Cells of all shapes and sizes are able to calculate the location of their middles in order to divide into two during mitosis. Minc et al. (2011) and Gibson et al. (2011) now show that simple mechanical models accurately predict cleavage-plane positioning, and that geometrical interactions between neighboring cells are sufficient to generate ordered ...
openaire +2 more sources
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
, 2010 Monitoring Editor: M. Bishr Omary Focal adhesions (FAs) located at the ends of actin/myosin-containing contractile stress fibers form tight connections between fibroblasts and their underlying extracellular matrix.
Lilli Winter +7 more
core +1 more source
Dynamics of a high-Reynolds-number bubble rising within a thin gap [PDF]
, 2012 We report an experimental analysis of path and shape oscillations of an air bubble of diameter d rising in water at high Reynolds number in a vertical Hele-Shaw cell of width h.
Billet, Anne-Marie +3 more
core +1 more source
A Compound Loss Function With Shape Aware Weight Map for Microscopy Cell Segmentation
, 2022 Microscopy cell segmentation is a crucial step in biological image analysis and a challenging task. In recent years, deep learning has been widely used to tackle this task, with promising results. A critical aspect of training complex neural networks for
Meijering, E +5 more
core +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
HLA-DR15 molecules jointly shape an autoreactive T cell repertoire in multiple sclerosis [PDF]
, 2020 The HLA-DR15 haplotype is the strongest genetic risk factor for multiple sclerosis (MS), but our understanding of how it contributes to MS is limited.
Martin, Roland +29 more
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Bacterial Evolution in High-Osmolarity Environments
mBio, 2020 Bacteria must maintain a cytosolic osmolarity higher than that of their environment in order to take up water. High-osmolarity environments therefore present formidable stress to bacteria. To explore the evolutionary mechanisms by which bacteria adapt to
Spencer Cesar +7 more
doaj +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source