Results 61 to 70 of about 14,296,855 (364)

Genomewide phenotypic analysis of growth, cell morphogenesis, and cell cycle events in Escherichia coli

open access: yesMolecular Systems Biology, 2018
Cell size, cell growth, and cell cycle events are necessarily intertwined to achieve robust bacterial replication. Yet, a comprehensive and integrated view of these fundamental processes is lacking. Here, we describe an image‐based quantitative screen of
Manuel Campos   +5 more
doaj   +1 more source

Cell Shape and Cell Lineage Conversion

open access: yesThe Journal of Poultry Science, 2015
The organization of animal cells in vivo can be categorized as being either epithelial or mesenchymal. Inter-conversions between these two states, epithelial-mesenchymal transition (EMT) and mesenchymal-epithelial transition (MET), often represent key ...
Yukiko Nakaya, Guojun Sheng
doaj   +1 more source

A mechano-osmotic feedback couples cell volume to the rate of cell deformation

open access: yeseLife, 2022
Mechanics has been a central focus of physical biology in the past decade. In comparison, how cells manage their size is less understood. Here, we show that a parameter central to both the physics and the physiology of the cell, its volume, depends on a ...
Larisa Venkova   +15 more
doaj   +1 more source

Decoding Information in Cell Shape [PDF]

open access: yesCell, 2013
Shape is an indicator of cell health. But how is the information in shape decoded? We hypothesize that decoding occurs by modulation of signaling through changes in plasma membrane curvature. Using analytical approaches and numerical simulations, we studied how elongation of cell shape affects plasma membrane signaling.
Rangamani, Padmini   +9 more
openaire   +2 more sources

Intraoperative Collection of Ascitic Fluid With Intra‐ or Postoperative Reinfusion in Ovarian Cancer: Safety and Feasibility of a Roller Pumping Method

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients with ovarian cancer often present with massive ascites, leading to significant protein loss during surgical procedures. Although cell‐free concentrated ascites reinfusion therapy (CART) is used in palliative settings to mitigate protein loss, its application in intraoperative settings remains unexplored.
Yutaka Yoneoka   +7 more
wiley   +1 more source

Evolutionary rescue of spherical mreB deletion mutants of the rod-shape bacterium Pseudomonas fluorescens SBW25

open access: yeseLife
Maintenance of rod-shape in bacterial cells depends on the actin-like protein MreB. Deletion of mreB from Pseudomonas fluorescens SBW25 results in viable spherical cells of variable volume and reduced fitness.
Paul Richard J Yulo   +10 more
doaj   +1 more source

A High-Content Microscopy Screening Identifies New Genes Involved in Cell Width Control in Bacillus subtilis

open access: yesmSystems, 2021
How cells control their shape and size is a fundamental question of biology. In most bacteria, cell shape is imposed by the peptidoglycan (PG) polymeric meshwork that surrounds the cell.
Dimitri Juillot   +8 more
doaj   +1 more source

Cytokinesis: Robust cell shape regulation [PDF]

open access: yesSeminars in Cell & Developmental Biology, 2016
Cytokinesis, the final step of cell division, is a great example of robust cell shape regulation. A wide variety of cells ranging from the unicellular Dictyostelium to human cells in tissues proceed through highly similar, stereotypical cell shape changes during cell division.
Vasudha, Srivastava   +2 more
openaire   +2 more sources

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa   +3 more
wiley   +1 more source

Scaling of erythrocyte shape and nucleus size among squamate reptiles: reanalysis points to constrained, proportional rather than adaptive changes

open access: yesRoyal Society Open Science, 2023
Small erythrocytes might be beneficial for blood rheology, as they contribute less to blood viscosity than large erythrocytes. We predicted that rheological disadvantages of larger erythrocytes could be alleviated by relatively smaller nucleus size in ...
Stanisław Bury   +2 more
doaj   +1 more source

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