Results 71 to 80 of about 7,293,453 (311)

Multistability and dynamic transitions of intracellular Min protein patterns

Molecular Systems Biology, 2016
Cells owe their internal organization to self‐organized protein patterns, which originate and adapt to growth and external stimuli via a process that is as complex as it is little understood. Here, we study the emergence, stability, and state transitions
Fabai Wu, Jacob Halatek, Matthias Reiter, Enzo Kingma, Erwin Frey, Cees Dekker   +5 more
doaj   +1 more source

MreB filaments align along greatest principal membrane curvature to orient cell wall synthesis

eLife, 2018
MreB is essential for rod shape in many bacteria. Membrane-associated MreB filaments move around the rod circumference, helping to insert cell wall in the radial direction to reinforce rod shape.
Saman Hussain, Carl N Wivagg, Piotr Szwedziak, Felix Wong, Kaitlin Schaefer, Thierry Izoré, Lars D Renner, Matthew J Holmes, Yingjie Sun, Alexandre W Bisson-Filho, Suzanne Walker, Ariel Amir, Jan Löwe, Ethan C Garner   +13 more
doaj   +1 more source

Distinct roles of nonmuscle myosin II isoforms for establishing tension and elasticity during cell morphodynamics

eLife, 2021
Nonmuscle myosin II (NM II) is an integral part of essential cellular processes, including adhesion and migration. Mammalian cells express up to three isoforms termed NM IIA, B, and C. We used U2OS cells to create CRISPR/Cas9-based knockouts of all three
Kai Weißenbruch, Justin Grewe, Marc Hippler, Magdalena Fladung, Moritz Tremmel, Kathrin Stricker, Ulrich Sebastian Schwarz, Martin Bastmeyer   +7 more
doaj   +1 more source

A torsion test for the study of the large deformation recovery of shape memory polymers [PDF]

, 2011
A torsion device was designed and built for testing the shape fixity and shape recovery of shape memory polymers at large deformation. A simple thermal chamber was used to regulate the thermal environment during testing and a CCD camera was used for ...
GILORMINI, Pierre, DIANI, Julie, FREDY, Carole, Carole Frédy, Pierre Gilormini, REGNIER, Gilles, Julie Diani, ROUSSEAU, Ingrid, Ingrid Rousseau, Yannick Merckel, Gilles Régnier, MERCKEL, Yannick   +11 more
core   +1 more source

Ewing Sarcoma in Infants and Children Under 2 Years of Age: A French Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Ewing sarcoma, the second most common primary bone cancer in children, requires intensive treatment that may lead to significant long‐term sequelae, particularly in infants. We retrospectively analyzed data from 1621 French patients treated between 1988 and 2015 within the EW88/93/97 or EE99 trials, focusing on 17 infants diagnosed before 24 ...
Elodie Verdier, Nathalie Cozic, Marie‐Dominique Tabone, Gaelle Pierron, Perrine Marec‐Berard, Sarah Winter, Gabriel Revon‐Rivière, Cyril Lervat, Dominique Plantaz, Marie‐Pierre Castex, Gregory Guimard, Estelle Thebaud, Stephanie Proust, Laure Saumet, Natacha Entz‐Werle, Sophie Taque, Cécile Vérité, Marta Jimenez, Nathalie Gaspar   +18 more
wiley   +1 more source

The Polygonal Cell Shape and Surface Protein Layer of Anaerobic Methane-Oxidizing Methylomirabilislanthanidiphila Bacteria

Frontiers in Microbiology, 2021
Methylomirabilis bacteria perform anaerobic methane oxidation coupled to nitrite reduction via an intra-aerobic pathway, producing carbon dioxide and dinitrogen gas. These diderm bacteria possess an unusual polygonal cell shape with sharp ridges that run
Lavinia Gambelli, Lavinia Gambelli, Lavinia Gambelli, Rob Mesman, Wouter Versantvoort, Christoph A. Diebolder, Andreas Engel, Wiel Evers, Wiel Evers, Mike S. M. Jetten, Martin Pabst, Bertram Daum, Bertram Daum, Laura van Niftrik   +13 more
doaj   +1 more source

Cell Shape, Cytoskeletal Tension, and RhoA Regulate Stem Cell Lineage Commitment [PDF]

, 2004
Commitment of stem cells to different lineages is regulated by many cues in the local tissue microenvironment. Here we demonstrate that cell shape regulates commitment of human mesenchymal stem cells (hMSCs) to adipocyte or osteoblast fate. hMSCs allowed
Bhadriraju, Kiran, Pirone, Dana M, Nelson, Celeste M, Chen, Christopher S, McBeath, Rowena   +4 more
core   +1 more source

Safety and Effectiveness of a High‐Dose, Tailored Tissue Plasminogen Activator Therapy Protocol: A Joint Pediatric Hematology and Cardiac ICU Quality Improvement Initiative Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric thromboembolism is increasingly encountered in critical care. Systemic thrombolysis with tissue plasminogen activator (tPA) facilitates vessel or valve patency, yet pediatric‐specific protocols remain undefined, and safety concerns persist. Objective To evaluate the efficacy and safety of a tailored, prolonged systemic tPA
Eran Shostak, Oded Gilad, Yael Feinstein, Sigal Nakav, Ofer Schiller, Joanne Yacobovich   +5 more
wiley   +1 more source

Wnt Signaling Induces Asymmetric Dynamics in the Actomyosin Cortex of the C. elegans Endomesodermal Precursor Cell

Frontiers in Cell and Developmental Biology, 2021
During asymmetrical division of the endomesodermal precursor cell EMS, a cortical flow arises, and the daughter cells, endodermal precursor E and mesodermal precursor MS, have an enduring difference in the levels of F-actin and non-muscular myosin ...
Francesca Caroti, Wim Thiels, Michiel Vanslambrouck, Rob Jelier   +3 more
doaj   +1 more source

Mechanisms shaping cell membranes [PDF]

Current Opinion in Cell Biology, 2014
Membranes of intracellular organelles are characterized by large curvatures with radii of the order of 10-30nm. While, generally, membrane curvature can be a consequence of any asymmetry between the membrane monolayers, generation of large curvatures requires the action of mechanisms based on specialized proteins.
Kozlov, Michael M, Campelo, Felix, Liska, Nicole, Chernomordik, Leonid V, Marrink, Siewert J, McMahon, Harvey T   +5 more
openaire   +3 more sources