Results 21 to 30 of about 224,353 (263)

Cruciate Ligament Cell Sheets Can Be Rapidly Produced on Thermoresponsive poly(glycidyl ether) Coating and Successfully Used for Colonization of Embroidered Scaffolds

Cells, 2021
Anterior cruciate ligament (ACL) cell sheets combined with biomechanically competent scaffolds might facilitate ACL tissue engineering. Since thermoresponsive polymers allow a rapid enzyme-free detachment of cell sheets, we evaluated the applicability of
Ingrid Zahn, Daniel David Stöbener, Marie Weinhart, Clemens Gögele, Annette Breier, Judith Hahn, Michaela Schröpfer, Michael Meyer, Gundula Schulze-Tanzil   +8 more
doaj   +1 more source

Novel Cell Therapy Using Mesenchymal Stromal Cell Sheets for Medication-Related Osteonecrosis of the Jaw

Frontiers in Bioengineering and Biotechnology, 2022
Despite medication-related osteonecrosis of the jaw (MRONJ) being first reported in 2003, the optimal treatment and prevention modalities for MRONJ are not clear.
Nobuyuki Kaibuchi, Nobuyuki Kaibuchi, Takanori Iwata, Takanori Iwata, Yoko Kawase Koga, Toshihiro Okamoto   +5 more
doaj   +1 more source

Zonal-Layered Chondrocyte Sheets for Repairment of Full-Thickness Articular Cartilage Defect: A Mini-Pig Model

Biomedicines, 2021
The cell sheet technique is a promising approach for tissue engineering, and the present study is aimed to determine a better configuration of cell sheets for cartilage repair.
Po-Chih Shen, Cheng-Chang Lu, Shih-Hsiang Chou, Zi-Miao Liu, Shu-Jem Su, Yin-Chun Tien   +5 more
doaj   +1 more source

Controlled Thin Polydimethylsiloxane Membrane with Small and Large Micropores for Enhanced Attachment and Detachment of the Cell Sheet

Membranes, 2022
Polydimethylsiloxane (PDMS) membranes can allow the precise control of well-defined micropore generation. A PDMS solution was mixed with a Rushton impeller to generate a large number of microbubbles. The mixed solution was spin-coated on silicon wafer to
Yeongseok Jang, Hyojae Kim, Jinmu Jung, Jonghyun Oh   +3 more
doaj   +1 more source

Cell Sheets Restore Secretory Function in Wounded Mouse Submandibular Glands

Cells, 2020
Thermoresponsive cell culture plates release cells as confluent living sheets in response to small changes in temperature, with recovered cell sheets retaining functional extracellular matrix proteins and tight junctions, both of which indicate formation
Harim T. dos Santos, Kyungsook Kim, Teruo Okano, Jean M. Camden, Gary A. Weisman, Olga J. Baker, Kihoon Nam   +6 more
doaj   +1 more source

Decellularised tissues obtained by a CO2-philic detergent and supercritical CO2 [PDF]

European Cells & Materials, 2018
Tissue decellularisation has gained much attention in regenerative medicine as an alternative to synthetic materials. In decellularised tissues, biological cues can be maintained and provide cellular environments still unmet by synthetic materials ...
J Antons, MGM Marascio, P Aeberhard, G Weissenberger, N Hirt-Burri, LA Applegate, PE Bourban, DP Pioletti   +7 more
doaj   +1 more source

Efficient and Consistent Orthotopic Osteosarcoma Model by Cell Sheet Transplantation in the Nude Mice for Drug Testing

Frontiers in Bioengineering and Biotechnology, 2021
Osteosarcoma is a big challenge on clinical treatment. The breakthrough associated with osteosarcoma in basic research and translational research depends on the reliable establishment of an animal model, whereby mice are frequently used.
Hongwei Wu, Zhengxi He, Zhengxi He, Xianan Li, Xuezheng Xu, Wu Zhong, Jie Bu, Gang Huang   +7 more
doaj   +1 more source

Sustained Oscillations of Epithelial Cell Sheets [PDF]

Biophysical Journal, 2018
Abstract Morphological changes during development, tissue repair, and disease largely rely on coordinated cell movements and are controlled by the tissue environment. Epithelial cell sheets are often subjected to large scale deformation during tissue formation. The active mechanical environment in which epithelial cells operate have the
Peyret, Grégoire, Mueller, Romain, D’alessandro, Joseph, Begnaud, Simon, Marcq, Philippe, Mège, René-Marc, Yeomans, Julia, Doostmohammadi, Amin, Ladoux, Benoit   +8 more
openaire   +5 more sources

Phenotypic traits of mesenchymal stem cell sheets fabricated by temperature-responsive cell culture plate: structural characteristics of MSC sheets

Stem Cell Research & Therapy, 2019
Background In most stem cell therapy strategies reported to date, stem cells are introduced to damaged tissue sites to repair and regenerate the original tissue structure and function.
Mitsuyoshi Nakao, Kyungsook Kim, Kenichi Nagase, David W. Grainger, Hideko Kanazawa, Teruo Okano   +5 more
doaj   +1 more source

Chondroprotective Effects of Chondrogenic Differentiated Adipose-Derived Mesenchymal Stem Cells Sheet on Degenerated Articular Cartilage in an Experimental Rabbit Model

Bioengineering, 2023
Adipose-derived stem cells (ADSCs) have been studied for many years as a therapeutic option for osteoarthritis (OA); however, their efficacy remains insufficient.
Atsushi Taninaka, Tamon Kabata, Katsuhiro Hayashi, Yoshitomo Kajino, Daisuke Inoue, Takaaki Ohmori, Ken Ueoka, Yuki Yamamuro, Tomoyuki Kataoka, Yoshitomo Saiki, Yu Yanagi, Musashi Ima, Takahiro Iyobe, Hiroyuki Tsuchiya   +13 more
doaj   +1 more source