Results 31 to 40 of about 224,353 (263)

Experimental Study on the Bone Morphogenetic Protein 1-Modified Bone Marrow Mesenchymal Stem Cell Sheets to Promote Mandibular Distraction Osteogenesis

open access: yesFrontiers in Surgery, 2022
ObjectiveThe present study aims to increase the concentration of genetically modified bone marrow mesenchymal stem cells (BMSCs) in the distraction osteogenesis (DO) interstitial space and induce the conversion of BMSCs to osteoblasts to improve the ...
Zhong-Ping Su   +7 more
doaj   +1 more source

Novel nanofibrous membrane‐supporting stem cell sheets for plasmid delivery and cell activation to accelerate wound healing

open access: yesBioengineering & Translational Medicine, 2022
The integration of biomaterials with cells for high overall performances is vitally important in tissue engineering, as scaffold‐free cell sheet lacks enough mechanical performance and cell viability while cell‐free scaffold possesses limited biological ...
Yanxia Zhu   +8 more
doaj   +1 more source

Measuring Adhesion Force of a Cell Sheet by the Ninety-degree Peel Test Using a Multi Hook Type Fixture

open access: yesJournal of Biomechanical Science and Engineering, 2013
In this study, we report measurements of the adhesion force of a cell sheet made by applying the ninety-degree peel test. The ninety-degree peel test has been applied to general sheet materials and its procedure is defined by the International Standard ...
Kaoru UESUGI   +6 more
doaj   +1 more source

Cell sheet tissue engineering: Cell sheet preparation, harvesting/manipulation, and transplantation

open access: yesJournal of Biomedical Materials Research Part A, 2019
AbstractCell sheet tissue engineering is a concept for creating transplantable two‐dimensional (2D) and three‐dimensional (3D) tissues and organs. This review describes three elements of cell sheet tissue engineering in terms of the chemical and physical effects of material surfaces and the interfacial properties of cell sheets: preparation, harvesting/
Jun Kobayashi   +3 more
openaire   +3 more sources

Nanotechnology Approaches in Tackling Cardiovascular Diseases

open access: yesMolecules, 2019
Cardiovascular diseases have continued to remain a leading cause of mortality and morbidity worldwide. Poor proliferation capability of adult cardiomyocytes disables the heart from regenerating new myocardium after a myocardial ischaemia event and ...
Ray Putra Prajnamitra   +4 more
doaj   +1 more source

Influence of Human Platelet Lysate on Extracellular Matrix Deposition and Cellular Characteristics in Adipose-Derived Stem Cell Sheets

open access: yesFrontiers in Cell and Developmental Biology, 2020
Adipose-derived stem cell (ASC) is a valuable source of cell therapy. By stimulating extracellular matrix (ECM) secretion, ASC sheets can be fabricated with enhanced regenerative capabilities.
Nai-Chen Cheng   +3 more
doaj   +1 more source

Towards clinical translation of the cell sheet engineering: Technological aspects

open access: yesSmart Materials in Medicine, 2023
Cell sheet engineering is a rapidly growing field of tissue engineering and regenerative medicine. The ease of cell sheet obtainment techniques and the resulting unique characteristics and microenvironment of these multicellular structures give rise to ...
Irina M. Zurina   +5 more
doaj   +1 more source

Infantile Central Nervous System Juvenile Xanthogranuloma With Somatic CSF1R Mutation Responsive to Imatinib Monotherapy

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Juvenile xanthogranuloma (JXG) of the central nervous system (CNS) is a rare non‐Langerhans cell histiocytosis. CSF1R mutations have been reported for peripheral JXG, but not in CNS JXG. A 3‐month‐old male presented with fever, lymphadenopathy, and macrocephaly with bulging fontanelles.
Sima Vazquez   +8 more
wiley   +1 more source

Cell sheet transplantation prevents inflammatory adhesions: A new treatment for adhesive otitis media

open access: yesRegenerative Therapy, 2021
Introduction: We developed a new treatment method that combines tympanoplasty with transplantation of autologous cultured nasal mucosal epithelial cell sheets to regenerate the mucosa of patients with adhesive otitis media, which has been difficult to ...
Kazuhisa Yamamoto   +6 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

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