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Sphingolipids and cell signalling

Journal of Inherited Metabolic Disease, 1998
AbstractThe sphingolipid storage disorders constitute a group of inherited metabolic disorders in which the structure of the stored sphingolipid and the corresponding genetic defect have been established. However, the pathological mechanism(s) behind the disorders has not been fully elucidated.
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Cells in search of a signal

Nature Cell Biology, 1999
During development, cells communicate by sending and receiving signals over long distances. New findings indicate that target cells may pick up signals by projecting long cytoplasmic extensions to the point at which the signals are produced.
Morata, G, Basler, K
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Cell signaling - is it new?

IEEE Engineering in Medicine and Biology Magazine, 2003
In these days of tissue engineering the term "cell signaling" is encountered frequently, and it refers to an effect that one type of cell produces on an adjacent or distant but different cell types. In most cases the effect is mediated by a chemical messenger.
L A, Geddes, R A, Roeder
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Cell–cell signaling in the shoot meristem

Current Opinion in Plant Biology, 2001
The shoot meristem is a proliferating, changing cell population yet displays a stable organization. Recent studies have addressed how signaling processes coordinate the behaviour of shoot meristem cells.
Haecker, Achim, Laux, Thomas
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Adenosine Signaling in Glioma Cells

2012
Purines and pyrimidines are fundamental signaling molecules in controlling the survival and proliferation of astrocytes, as well as in mediating cell-to-cell communication between glial cells and neurons in the healthy brain. The malignant transformation of astrocytes towards progressively more aggressive brain tumours (from astrocytoma to anaplastic ...
S. Ceruti, M. Abbracchio
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Cell–cell Signaling in the Neurovascular Unit

Neurochemical Research, 2007
Historically, the neuron has been the conceptual focus for almost all of neuroscience research. In recent years, however, the concept of the neurovascular unit has emerged as a new paradigm for investigating both physiology and pathology in the CNS. This concept proposes that a purely neurocentric focus is not sufficient, and emphasizes that all cell ...
Josephine, Lok   +6 more
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Ca2+ and cell signalling in guard cells

Seminars in Cell Biology, 1993
Abscisic acid (ABA)-induced stomatal closure involves two different signalling chains, only one of which is Ca(2+)-dependent. ABA induces deactivation of the inward K+ channel and activation of an inward 'background' current, changes also produced by high cytoplasmic Ca2+ or injection of inositol 1,4,5-trisphosphate.
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Methods in Cell-to-Cell Signaling in Salmonella

2007
Many bacteria can sense their population density. This has been termed "quorum sensing." The bacteria use this information to coordinate their behavior, essentially behaving as multicellular organisms. The paradigm of Gram-negative quorum sensing is the LuxL/LuxR-type system employed by Vibriofischeri to regulate luminescence.
Brian M M, Ahmer   +3 more
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Fluorescent Probes of Cell Signaling

Annual Review of Neuroscience, 1989
Fluorescence has long been recognized as a powerful tool for probing biological structure and function. Because probe molecules can be very much more fluorescent than the constituents of most biological specimens, the signal for the exogenous fluorophores can be measured continuously and nondestructively with excellent spatial and temporal resolution ...
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Cell-Cell Signalling

1985
The concept of cellular cooperation has long been recognized as being fundamental in several physio-pathological systems such as: 1) In immunology, B-cells require interaction with T-cells to induce antibody responses. 2) The development of atherosclerotic processes involves interactions between blood cells and vascular cells. 3) Inflammatory reactions
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