Results 51 to 60 of about 2,240,723 (318)
Nature Communications, 2021 Cells experience various osmotic perturbation, but cellular osmosensing mechanisms remain obscure. Here, the authors report that cells recognize osmotic stress from the inside through macromolecular crowding-driven and poly(ADP-ribose)-conditioned liquid–
Kengo Watanabe +7 more
doaj +1 more source
K+ Channel Tetramerization Domain 5 (KCTD5) Protein Regulates Cell Migration, Focal Adhesion Dynamics and Spreading through Modulation of Ca2+ Signaling and Rac1 Activity [PDF]
, 2020 Cell migration is critical for several physiological and pathophysiological processes. It depends on the coordinated action of kinases, phosphatases, Rho-GTPases proteins, and Ca2+ signaling.
Riquelme, Denise +11 more
core +1 more source
Store Operated Calcium Entry in Cell Migration and Cancer Metastasis [PDF]
, 2021 Ca2+ signaling is ubiquitous in eukaryotic cells and modulates many cellular events including cell migration. Directional cell migration requires the polarization of both signaling and structural elements.
Khaled Machaca, Ayat S. Hammad
core +1 more source
Signal Processing On Cell Complexes
ICASSP 2022 - 2022 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP), 2022 5 pages, 3 ...
T. Mitchell Roddenberry +2 more
openaire +2 more sources
Hematopoietic Signaling Mechanism Revealed from a Stem/Progenitor Cell Cistrome [PDF]
, 2018 Thousands of cis-elements in genomes are predicted to have vital functions. Although conservation, activity in surrogate assays, polymorphisms, and disease mutations provide functional clues, deletion from endogenous loci constitutes the gold-standard ...
Rajendran Sanalkumar +11 more
core +1 more source
Cellular MicrobiologyTrial Registration: ClinicalTrials.gov identifier: NCT01473524 ...
Gayatri Reghu +3 more
doaj +1 more source
Nature Communications, 2017 Ubiquitin ligase TRAF6 catalyzes assembly of free polyubiquitin chains for TAK1 activation in the IL-1R/TLR pathways, but the mechanism underlying its processivity is unclear.
Lin Hu +11 more
doaj +1 more source
WAC Promotes Polo-like Kinase 1 Activation for Timely Mitotic Entry
Cell Reports, 2018 Summary: The key mitotic regulator Polo-like kinase 1 (Plk1) is activated during G2 phase by Aurora A kinase (AurkA)-mediated phosphorylation of its activation loop, which is important for timely mitotic entry.
Feifei Qi +12 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger +7 more
wiley +1 more source
On the emergence and evolution of artificial cell signaling networks [PDF]
, 2007 This PhD project is concerned with the evolution of Cell Signaling Networks (CSNs) in silico. CSNs are complex biochemical networks responsible for the coordination of cellular activities.
Decraene, James
core