Results 31 to 40 of about 2,240,723 (318)
Evolving artificial cell signaling networks using molecular classifier systems [PDF]
, 2006 Nature is a source of inspiration for computational techniques which have been successfully applied to a wide variety of complex application domains. In keeping with this we examine Cell Signaling Networks (CSN) which are chemical networks responsible ...
James Decraene +5 more
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The p53 family member p73 in the regulation of cell stress response
Biology Direct, 2021 During oncogenesis, cells become unrestrictedly proliferative thereby altering the tissue homeostasis and resulting in subsequent hyperplasia. This process is paralleled by resumption of cell cycle, aberrant DNA repair and blunting the apoptotic program ...
Julian M. Rozenberg +13 more
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Role of the Tumor Microenvironment in Regulating Pancreatic Cancer Therapy Resistance
Cells, 2022 Pancreatic cancer has a notoriously poor prognosis, exhibits persistent drug resistance, and lacks a cure. Unique features of the pancreatic tumor microenvironment exacerbate tumorigenesis, metastasis, and therapy resistance. Recent studies emphasize the
Daiyong Deng +3 more
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CLE peptide signaling during plant development [PDF]
, 2009 Peptide signaling in plants is a rapid developing area of research which focuses on so called peptide hormones. These signaling molecules are utilized for inter-cellular communication in different developmental processes, beside the usage of the more ...
Fiers, M.A. +3 more
core +1 more source
Xmrks the Spot: Fish Models for Investigating Epidermal Growth Factor Receptor Signaling in Cancer Research [PDF]
, 2021 Studies conducted in several fish species, e.g., Xiphophorus hellerii (green swordtail) and Xiphophorus maculatus (southern platyfish) crosses, Oryzias latipes (medaka), and Danio rerio (zebrafish), have identified an oncogenic role for the receptor ...
Jerry D. Monroe +2 more
core +1 more source
Automated single-molecule imaging in living cells
Nature Communications, 2018 Large scale live cell screens often lack single-molecule resolution. Here the authors present an artificial intelligence-assisted TIRF microscope with automated cell searching and focusing, and use it for high-throughput single-molecule imaging of EGFR ...
Masato Yasui +4 more
doaj +1 more source
Cell Signaling in Neurodegeneration
International Journal of Molecular Sciences, 2021 Neurodegenerative diseases are characterized by the progressive loss of specific subsets of neurons [...]
openaire +2 more sources
Cold Spring Harbor Perspectives in Biology, 2015 In multicellular organisms, cell death is a critical and active process that maintains tissue homeostasis and eliminates potentially harmful cells. There are three major types of morphologically distinct cell death: apoptosis (type I cell death), autophagic cell death (type II), and necrosis (type III).
Douglas R, Green, Fabien, Llambi
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A20 deubiquitinase controls PGC-1α expression in the adipose tissue
Lipids in Health and Disease, 2018 Background Peroxisome proliferator-activated receptor γ coactivator- 1alpha (PGC-1α) plays an important role in whole body metabolism and, particularly in glucose homeostasis.
Bruna Bombassaro +8 more
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Cell Death and Disease, 2020 Radiotherapy is commonly used as a cytotoxic treatment of a wide variety of tumors. Interestingly, few case reports underlined its potential to induce immune-mediated abscopal effects, resulting in regression of metastases, distant from the irradiated ...
Sandy Adjemian +13 more
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