Results 21 to 30 of about 2,233,123 (318)

Guard Cell Signaling [PDF]

open access: yesCell, 2001
The plant hormone abscisic acid (ABA) regulates the aperture of the stomatal pore. The recent identification of new intermediates involved in ABA signaling suggests that this complex pathway is organized as a module-based network.
openaire   +2 more sources

Cell signaling and cancer [PDF]

open access: yesGenome Biology, 2007
A report on the Cancer Research UK London Research Institute Special Conference 'Signal Transduction', London, UK, 14-16 May 2007.
Bazigou, Eleni, Rallis, Charalampos
openaire   +3 more sources

NOTCH1 Signaling in Head and Neck Squamous Cell Carcinoma

open access: yes, 2020
Biomarker-driven targeted therapies are lacking for head and neck squamous cell carcinoma (HNSCC), which is common and lethal. Efforts to develop such therapies are hindered by a genomic landscape dominated by the loss of tumor suppressor function ...
Faye M. Johnson   +7 more
core   +1 more source

Role of the Tumor Microenvironment in Regulating Pancreatic Cancer Therapy Resistance

open access: yesCells, 2022
Pancreatic cancer has a notoriously poor prognosis, exhibits persistent drug resistance, and lacks a cure. Unique features of the pancreatic tumor microenvironment exacerbate tumorigenesis, metastasis, and therapy resistance. Recent studies emphasize the
Daiyong Deng   +3 more
doaj   +1 more source

Signaling in the crowded cell

open access: yesCurrent Opinion in Structural Biology, 2021
High-resolution technologies have clarified some of the principles underlying cellular actions. However, understanding how cells receive, communicate, and respond to signals is still challenging. Questions include how efficient regulation of assemblies, which execute cell actions at the nanoscales, transmits productively at micrometer scales ...
Ruth Nussinov   +2 more
openaire   +2 more sources

Evolving artificial cell signaling networks using molecular classifier systems [PDF]

open access: yes, 2006
Nature is a source of inspiration for computational techniques which have been successfully applied to a wide variety of complex application domains. In keeping with this we examine Cell Signaling Networks (CSN) which are chemical networks responsible ...
James Decraene   +5 more
core   +1 more source

The p53 family member p73 in the regulation of cell stress response

open access: yesBiology Direct, 2021
During oncogenesis, cells become unrestrictedly proliferative thereby altering the tissue homeostasis and resulting in subsequent hyperplasia. This process is paralleled by resumption of cell cycle, aberrant DNA repair and blunting the apoptotic program ...
Julian M. Rozenberg   +13 more
doaj   +1 more source

Automated single-molecule imaging in living cells

open access: yesNature Communications, 2018
Large scale live cell screens often lack single-molecule resolution. Here the authors present an artificial intelligence-assisted TIRF microscope with automated cell searching and focusing, and use it for high-throughput single-molecule imaging of EGFR ...
Masato Yasui   +4 more
doaj   +1 more source

Cell Signaling in Neurodegeneration

open access: yesInternational Journal of Molecular Sciences, 2021
Neurodegenerative diseases are characterized by the progressive loss of specific subsets of neurons [...]
openaire   +2 more sources

The Significance of the Dysregulation of Canonical Wnt Signaling in Head and Neck Squamous Cell Carcinomas

open access: yes, 2020
The knowledge about the molecular alterations which are found in head and neck squamous cell carcinomas (HNSCC) has much increased in recent years. However, we are still awaiting the translation of this knowledge to new diagnostic and therapeutic options.
Jarosław Paluszczak
core   +1 more source

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