Results 11 to 20 of about 2,233,123 (318)
The Role of BANK1 in B Cell Signaling and Disease [PDF]
, 2021 The preparation of this review was funded by the Ministerio de Economia y Competitividad (now Ministerio de Ciencia e Innovacion) of the Government of Spain with number SAF2016-78631-P. G.G.H.
Gonzalo Gómez Hernández +5 more
core +1 more source
Hedgehog Signaling in Cortical Development [PDF]
, 2023 The Hedgehog (Hh) pathway plays a crucial role in embryonic development, acting both as a morphogenic signal that organizes tissue formation and a potent mitogenic signal driving cell proliferation.
Xuecai Ge +5 more
core +1 more source
Intrinsically Disordered Proteins Play Diverse Roles in Cell Signaling
, 2022 Signaling pathways allow cells to detect and respond to a wide variety of chemical (e.g. Ca2+ or chemokine proteins) and physical stimuli (e.g., sheer stress, light).
Uversky, Vladimir N. +2 more
core +1 more source
Journal of Neuroinflammation, 2021 Background Interleukin-6 (IL6) produced in the context of exercise acts in the hypothalamus reducing obesity-associated inflammation and restoring the control of food intake and energy expenditure.
Vanessa C. Bobbo +9 more
doaj +1 more source
Rhabdomyolysis attenuates activity of semicarbazide sensitive amine oxidase as the marker of nephropathy in diabetic rats [PDF]
The Ukrainian Biochemical Journal, 2022 Amine oxidases are involved in the progression of many diseases and their complications, including renal failure, due to the generation of the three toxic metabolites (H2O2, aldehydes, and ammonia) in the course of biogenic amines oxidative deamination ...
O. Hudkova +3 more
doaj +1 more source
Ubiquitylation and cell signaling [PDF]
The EMBO Journal, 2005 Ubiquitylation is an emerging mechanism implicated in a variety of nonproteolytic cellular functions. The attachment of a single ubiquitin (Ub) or poly-Ub (lysine 63) chains to proteins control gene transcription, DNA repair and replication, intracellular trafficking and virus budding.
Kaisa, Haglund, Ivan, Dikic
openaire +2 more sources
Proteomes, 2015 Gaining insight into normal cellular signaling and disease biology is a critical goal of proteomic analyses. The ability to perform these studies successfully to extract the maximum value and discovery of biologically relevant candidate biomarkers is ...
Matthew P. Stokes +8 more
doaj +1 more source
Cell Signaling: An overview [PDF]
Oncogene, 1998 Signal transduction is one of the fundamental processes of living cells being second in importance only to cell division. From the unicellular organism to multicellular organism, evolution has molded a diverse array of novel motifs and mechanisms to ensure that cells can eciently adapt to their environment.
openaire +2 more sources
CELL BIOLOGY AND SIGNALING [PDF]
Neuro-Oncology, 2010 The phylogenetically-conserved vertebrate transcription factor, NFIB, is an orchestrator of glial differentiation in the developing mammalian central nervous system. We found NFIB expression to be reduced in glioblastoma (GBM), the commonest and most lethal primary adult brain cancer, so investigated what effect increased expression of NFIB had on GBM.
M. Agarwal +200 more
openaire +3 more sources
, 2023 Cervical cancer is the most prevalent gynecological tumor among women worldwide. Although the incidence and mortality of cervical cancer have been declining thanks to the wide-scale implementation of cytological screening, it remains a major challenge in
Jun Zhang +5 more
core +1 more source