Results 91 to 100 of about 2,922,174 (317)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Small adipose-derived mesenchymal stromal cells exhibit longer telomeres and enhanced regenerative potential

open access: yesFrontiers in Bioengineering and Biotechnology
Younger, replicative cells with longer telomeres can enhance regenerative therapies, however, there is a lack of a standard method to assess telomere length in live cells.
Uldis Berzins   +12 more
doaj   +1 more source

Influence of the size of nanostructured metals on changes in the functional state of the cell and biological activity [PDF]

open access: diamond, 2020
D.G. Churilov   +4 more
openalex   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Efeito da densidade de mudas por célula e do volume da célula na produção de mudas e cultivo da rúcula Effect of seedlings density per cells and cells volume on seedlings production and yield of rocket press

open access: yesCiência e Agrotecnologia, 2004
O experimento foi conduzido em Ponta Grossa (PR) com o objetivo de avaliar o efeito da densidade de mudas por célula em diferentes bandejas na produção de mudas e no cultivo da rúcula.
Marie Yamamoto Reghin   +2 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

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