Results 101 to 110 of about 3,250,985 (308)

Assessment of Vibrational Non-Equilibrium Effect on Detonation Cell Size

open access: yes, 2017
To resolve the discrepancy between the numerical detonation cell size and experimental observations simulations are conducted with a detailed thermochemical reaction model for a premixed argon-diluted hydrogen-oxygen mixture. Four different scenarios are
Wen CH   +5 more
core   +1 more source

The Multiple Interactions of RUNX with the Hippo–YAP Pathway

open access: yes, 2021
The Hippo–YAP signaling pathway serves roles in cell proliferation, stem cell renewal/maintenance, differentiation and apoptosis. Many of its functions are central to early development, adult tissue repair/regeneration and not surprisingly, tumorigenesis
Chuang, Linda Shyue Huey   +3 more
core   +1 more source

Modeled Tracheidograms Disclose Drought Influence on Pinus sylvestris Tree-Rings Structure From Siberian Forest-Steppe

open access: yesFrontiers in Plant Science, 2018
Wood formation allows trees to adjust in a changing climate. Understanding what determine its adjustment is crucial to evaluate impacts of climatic changes on trees and forests growth.
Margarita I. Popkova   +9 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Stem cell growth and differentiation in Hydra attenuata [PDF]

open access: yes, 1979
Interstitial stem cells in Hydra are rapidly proliferating multipotent stem cells which continuously give rise to precursors for nerve and nematocyte differentiation.
Sproull, Frederick, David, Charles N.
core  

Accuracy and Reliability of Oral Exfoliative Cytology in Age Estimation: An Observational Study

open access: yesJournal of Pharmacy and Bioallied Sciences
Aim and Objectives: Age and gender identification are critical in forensic investigations, especially for unidentified human bodies. This study explores differences in nuclear size, nuclear area, and nuclear-cytoplasmic ratio between healthy individuals ...
Naseemoon Shaik   +6 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Clonal acquisition of the Ly49A NK cell receptor is dependent on the trans-acting factor TCF-1

open access: yes, 1999
Families of clonally expressed major histocompatibility complex (MHC) class I–specific receptors provide specificity to and regulate the function of natural killer (NK) cells.
van de Wetering, Marc   +16 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Integrated Functions of Pax3 and Pax7 in the Regulation of Proliferation, Cell Size and Myogenic Differentiation

open access: yes, 2009
Pax3 and Pax7 are paired-box transcription factors with roles in developmental and adult regenerative myogenesis. Pax3 and Pax7 are expressed by postnatal satellite cells or their progeny but are down regulated during myogenic differentiation.
Morgan, JE   +25 more
core   +1 more source

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