Results 211 to 220 of about 5,248,930 (285)

mRNA trafficking directs cell-size-scaling of mitochondria distribution and function

Bradbury JJ, Hulmes GE, Viswanathan R, Costa G, Lovegrove HE, Herbert SP.   +5 more
europepmc   +1 more source

Cell size differences affect photosynthetic capacity in a Mesoamerican and an Andean genotype of Phaseolus vulgaris L. [PDF]

Front Plant Sci
Egesa AO, Vallejos CE, Begcy K.
europepmc   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

More than a passive barrier: algal cell walls play an active role in determining cell shape, cell size, and organelle morphology. [PDF]

J Exp Bot
Hoffmann N.
europepmc   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Extending the G1 phase improves the production of lipophilic compounds in yeast by boosting enzyme expression and increasing cell size. [PDF]

Proc Natl Acad Sci U S A
Hao H, Yao M, Wang Y, Zhang C, Liu Z, Nielsen J, Shi S, Xiao W, Yuan Y.   +8 more
europepmc   +1 more source

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

FEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang, Lynn Kee, Alexander Gont, Jalna Meens, Fraser G. Ferens, Meredith S. Irwin, Laurie Ailles, Scott A. Yuzwa, Claire M. Robinson, Michael Ohh   +9 more
wiley   +1 more source

On the equivalence of demagnetization tensors as discrete cell size approaches zero in three-dimensional space. [PDF]

J Appl Phys
Liang H, Yan X.
europepmc   +1 more source

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source

Cell size, density, and nutrient dependency of unicellular algal gravitational sinking velocities. [PDF]

Sci Adv
Miettinen TP, Gomez AL, Wu Y, Wu W, Usherwood TR, Hwang Y, Roller BRK, Polz MF, Manalis SR.   +8 more
europepmc   +1 more source