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Bacterial cell size modulation along the growth curve across nutrient conditions
Nieto C, Igler C, Singh A.
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Chromatin Compaction Follows a Power Law Scaling with Cell Size from Interphase Through Mitosis
Stockinger P +4 more
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Mitochondrial dynamics regulate cell size in the developing cochlea
O’Sullivan JDB +5 more
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Cell size: Single cells illuminate the rules of cell size control
Current Biology, 2023A new study uses Chlamydomonas reinhardtii to understand how cell size homeostasis emerges from stochastic individual cell behaviors within a population. The authors find that a simple power law model was a poor predictor of cell size regulation; rather, it is better explained by a modified threshold model.
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Why size matters: altering cell size
Current Opinion in Genetics & Development, 2002Several genes involved in growth control have lately been demonstrated to exhibit more potent effects on cell size than on cell proliferation. Many of these genes direct protein and ribosomal synthesis, highlighting the interdependence between cell size and macromolecular content.
Leslie J, Saucedo, Bruce A, Edgar
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Epithelial homeostasis: Cell size shapes cell fate
Current Biology, 2023A new study shows that cell size, in conjunction with specific signaling pathways, controls apoptosis within developing tissues. Cells with smaller sizes and relatively smaller sizes compared to their neighbors exhibit an increased likelihood of undergoing apoptosis. These processes are regulated by the Hippo/YAP and Notch pathways, respectively.
Xiang, Teng, Yusuke, Toyama
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