Results 91 to 100 of about 319,319 (301)

Sorting cells by their dynamical properties [PDF]

Scientific Reports, 2016
AbstractRecent advances in cell sorting aim at the development of novel methods that are sensitive to various mechanical properties of cells. Microfluidic technologies have a great potential for cell sorting; however, the design of many micro-devices is based on theories developed for rigid spherical particles with size as a separation parameter ...
Henry, Ewan, Holm, Stefan H., Zhang, Zunmin, Beech, Jason P., Tegenfeldt, Jonas O., Fedosov, Dmitry, Gompper, Gerhard   +6 more
openaire   +3 more sources

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Position paper on the existing selection procedure in Germany for the degree program human medicine – interim evaluation after four years. Position paper of the student selection (ASA) in the DACH Association for Medical Education (GMA)

GMS Journal for Medical Education
Four years after the entry into force of the new allocation rules, this position paper by the Committee on Student Selection of the GMA presents an initial interim assessment of the intended aspects of aptitude, public welfare considerations, and the ...
Brigitte Müller-Hilke, Kirsten Gehlhar
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Potential biomarkers for early periodontal inflammation: investigating CD5+ B cells, salivary cytokines and oral microbiome

Scientific Reports
Periodontitis is a highly prevalent chronic inflammatory disease that causes progressive destruction of the tooth-supporting apparatus and is linked to multiple systemic disorders.
Elisabeth Clara Gottschalk, Oleksandra Chabanovska, Praveen Vasudevan, Israel Barrantes, Bernd Kreikemeyer, Wendy Bergmann-Ewert, Robby Engelmann, Brigitte Müller-Hilke, Hermann Lang   +8 more
doaj   +1 more source

Improving the biosafety of cell sorting by adaptation of a cell sorting system to a biosafety cabinet [PDF]

Cytometry Part A, 2005
AbstractBackground:The jet‐in‐air cell sorters currently available are not very suitable for sorting potentially biohazardous material under optimal conditions because they do not protect operators and samples as recommended in the guidelines for safe biotechnology.
Klaus, Lennartz, Mengji, Lu, Michael, Flasshove, Thomas, Moritz, Uwe, Kirstein   +4 more
openaire   +2 more sources

The developmental cell biology of Trypanosoma brucei [PDF]

, 2005
Trypanosoma brucei provides an excellent system for studies of many aspects of cell biology, including cell structure and morphology, organelle positioning, cell division and protein trafficking. However, the trypanosome has a complex life cycle in which
Matthews, Keith R; id_orcid, Keith R. Matthews   +1 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source