Results 71 to 80 of about 5,022,243 (208)
Scientific ReportsPeriodontitis is a highly prevalent chronic inflammatory disease that causes progressive destruction of the tooth-supporting apparatus and is linked to multiple systemic disorders.
Elisabeth Clara Gottschalk +8 more
doaj +1 more source
Bicomponent sorting algorithms
, 2023 The possibilities of improving sorting time parameters through preprocessing by stochastic sorting were investigated. The hypothesis that two-component stochastic + classical sorting outperforms classic one-component sorting in terms of time efficiency ...
Halanin, K. K. +4 more
core
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
, 2009 Optical trapping of particles has become a powerful non-mechanical and nondestructive technique for precise particle positioning. The manipulation of particles in the evanescent field of a channel waveguide potentially allows for sorting and trapping of ...
Mohamad Shahimin, Mukhzeer
core +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Revolutionizing Stem Cell Sorting with Machine Learning: A Review of Trends, Tools, and Future Directions [PDF]
Iranian Journal of Medical SciencesStem cells are critical tools in regenerative medicine, large-scale cell production, drug discovery, and cell-based therapies, making their precise identification and sorting essential for advancing both research and clinical applications.
Marziyeh Mousazadeh +6 more
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Applications of microfluidic chips in optical manipulation & photoporation [PDF]
, 2010 Integration and miniaturisation in electronics has undoubtedly revolutionised the modern world. In biotechnology, emerging lab-on-a-chip (LOC) methodologies promise all-integrated laboratory processes, to perform complete biochemical or medical ...
Marchington, Robert F.
core +2 more sources
Clostridium difficile has a single sortase, SrtB, that can be inhibited by small-molecule inhibitors. [PDF]
, 2014 BACKGROUND: Bacterial sortases are transpeptidases that covalently anchor surface proteins to the peptidoglycan of the Gram-positive cell wall. Sortase protein anchoring is mediated by a conserved cell wall sorting signal on the anchored protein ...
Valiente, Esmeralda +7 more
core +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source