Results 51 to 60 of about 591,980 (296)

Intact DNA purified from flow-sorted nuclei unlocks the potential of next-generation genome mapping and assembly in Solanum species

MethodsX, 2018
Next-generation genome mapping through nanochannels (Bionano optical mapping) of plant genomes brings genome assemblies to the ‘nearly-finished’ level for reliable and detailed gene annotations and assessment of structural variations.
Paola Gaiero, Hana Šimková, Jan Vrána, Federico F. Santiñaque, Beatriz López-Carro, Gustavo A. Folle, José van de Belt, Sander A. Peters, Jaroslav Doležel, Hans de Jong   +9 more
doaj   +1 more source

Large-scale simulations of biological cell sorting driven by differential adhesion follow diffusion-limited domain coalescence regime.

PLoS Computational Biology, 2021
Cell sorting, whereby a heterogeneous cell mixture segregates and forms distinct homogeneous tissues, is one of the main collective cell behaviors at work during development.
Marc Durand
doaj   +1 more source

High-throughput continuous dielectrophoretic separation of neural stem cells. [PDF]

, 2019
We created an integrated microfluidic cell separation system that incorporates hydrophoresis and dielectrophoresis modules to facilitate high-throughput continuous cell separation. The hydrophoresis module consists of a serpentine channel with ridges and
Adams, Tayloria NG, Aghaamoo, Mohammad, Flanagan, Lisa A, Jiang, Alan YL, Lee, Abraham P, Lee, Do-Hyun, Yale, Andrew R   +6 more
core   +1 more source

Survival Outcomes and Complications Among Canadian Children With Retinoblastoma: A Population‐Based Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine, Ofélie Trudeau‐Ferrin, Caroline Laverdière, Patrick Hamel, Rosanne Superstein, Bénédicte Koukoui, Carole Provost, Paul C. Nathan, Vijay Ramaswamy, Furqan Shaikh, Brenda Gallie, Ashwin Mallipatna, Stephanie Kletke, Helen Dimaras, Hallie Coltin   +14 more
wiley   +1 more source

Transcriptome analysis of classical blood cells reveals downregulation of pro-inflammatory genes in the classical monocytes of long COVID patients

Frontiers in Immunology
IntroductionDespite extensive research, the pathogenesis and predispositions underlying long COVID (long-term coronavirus disease 2019) remain poorly understood.MethodsTo address this, we analyzed the immunological landscapes of 44 patients with long ...
Florian Fricke, Franz Mai, Christine Wossidlo, Felix Steinbeck, Felix Steinbeck, Wendy Bergmann-Ewert, Marcel Kordt, Karin Kraft, Britta Müller, Emil C. Reisinger, Brigitte Müller-Hilke   +10 more
doaj   +1 more source

Upgraded User-Friendly Image-Activated Microfluidic Cell Sorter Using an Optimized and Fast Deep Learning Algorithm

Micromachines, 2022
Image-based cell sorting is essential in biological and biomedical research. The sorted cells can be used for downstream analysis to expand our knowledge of cell-to-cell differences. We previously demonstrated a user-friendly image-activated microfluidic
Keondo Lee, Seong-Eun Kim, Seokho Nam, Junsang Doh, Wan Kyun Chung   +4 more
doaj   +1 more source

Transcriptional landscape of epithelial and immune cell populations revealed through FACS-seq of healthy human skin. [PDF]

, 2017
Human skin consists of multiple cell types, including epithelial, immune, and stromal cells. Transcriptomic analyses have previously been performed from bulk skin samples or from epithelial and immune cells expanded in cell culture.
Ahn, Richard S, Arron, Sarah T, Chang, David S, Gupta, Rashmi, Lai, Kevin, Lee, Kristina M, Liao, Wilson, Nititham, Joanne, Rosenblum, Michael, Taravati, Keyon   +9 more
core   +1 more source

Versatile phenotype-activated cell sorting [PDF]

Science Advances, 2020
Versatile high-throughput method can isolate single cells based on spatiotemporal phenotypes.
Jihwan Lee, Zhuohe Liu, Peter H. Suzuki, John F. Ahrens, Shujuan Lai, Xiaoyu Lu, Sihui Guan, François St-Pierre   +7 more
openaire   +3 more sources

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Microfluidics for Peptidomics, Proteomics, and Cell Analysis

Nanomaterials, 2021
Microfluidics is the advanced microtechnology of fluid manipulation in channels with at least one dimension in the range of 1–100 microns. Microfluidic technology offers a growing number of tools for manipulating small volumes of fluid to control ...
Rui Vitorino, Sofia Guedes, João Pinto da Costa, Václav Kašička   +3 more
doaj   +1 more source