Results 41 to 50 of about 591,980 (296)

MECOM-associated syndrome: a heterogeneous inherited bone marrow failure syndrome with amegakaryocytic thrombocytopenia

open access: yesBlood Advances, 2018
: Heterozygous mutations in MECOM (MDS1 and EVI1 complex locus) have been reported to be causative of a rare association of congenital amegakaryocytic thrombocytopenia and radioulnar synostosis.
Manuela Germeshausen   +11 more
doaj   +1 more source

CCR2 macrophage response determines the functional outcome following cardiomyocyte transplantation

open access: yesGenome Medicine, 2023
Background The immune response is a crucial factor for mediating the benefit of cardiac cell therapies. Our previous research showed that cardiomyocyte transplantation alters the cardiac immune response and, when combined with short-term pharmacological ...
Praveen Vasudevan   +15 more
doaj   +1 more source

Multiparametric flow cytometry and cell sorting for the assessment of viable, injured, and dead bifidobacterium cells during bile salt stress [PDF]

open access: yes, 2002
Using a flow cytometry-based approach, we assessed the viability of Bifidobacterium lactis DSM 10140 and Bifidobacterium adolescentis DSM 20083 during exposure to bile salt stress.
Amor, K., Ben   +6 more
core   +2 more sources

DIE-RNA: A Reproducible Strategy for the Digestion of Normal and Injured Pancreas, Isolation of Pancreatic Cells from Genetically Engineered Mouse Models and Extraction of High Quality RNA

open access: yesFrontiers in Physiology, 2018
The isolation of ribonucleic acid (RNA) suitable for gene expression studies is challenging in the pancreas, due to its high ribonuclease activity. This is even more complicated during pancreatitis, a condition associated with inflammation and fibrosis ...
Mohamad Assi   +2 more
doaj   +1 more source

Computational modeling reveals that a combination of chemotaxis and differential adhesion leads to robust cell sorting during tissue patterning. [PDF]

open access: yesPLoS ONE, 2014
Robust tissue patterning is crucial to many processes during development. The "French Flag" model of patterning, whereby naïve cells in a gradient of diffusible morphogen signal adopt different fates due to exposure to different amounts of morphogen ...
Rui Zhen Tan, Keng-Hwee Chiam
doaj   +1 more source

Cell Cluster Sorting in Automated Differentiation of Patient-specific Induced Pluripotent Stem Cells Towards Blood Cells

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
Induced pluripotent stem cells (iPS cells) represent a particularly versatile stem cell type for a large array of applications in biology and medicine. Taking full advantage of iPS cell technology requires high throughput and automated iPS cell culture ...
Zhiyao Ma   +20 more
doaj   +1 more source

Modular Nucleic Acid Assembled p/MHC Microarrays for Multiplexed Sorting of Antigen-Specific T Cells [PDF]

open access: yes, 2009
The human immune system consists of a large number of T cells capable of recognizing and responding to antigens derived from various sources. The development of peptide-major histocompatibility (p/MHC) tetrameric complexes has enabled the direct ...
Bailey, Ryan C.   +12 more
core   +2 more sources

Intranuclear immunostaining-based FACS protocol from embryonic cortical tissue

open access: yesSTAR Protocols, 2021
Summary: Cell sorting can be used to purify cell populations for cell type-specific molecular probing. Fluorescence-activated cell sorting (FACS) coupled with high-throughput sequencing affords molecular signature identification for specific cell types ...
M. Sadman Sakib   +4 more
doaj   +1 more source

The case for absolute ligand discrimination : modeling information processing and decision by immune T cells [PDF]

open access: yes, 2015
Some cells have to take decision based on the quality of surroundings ligands, almost irrespective of their quantity, a problem we name "absolute discrimination". An example of absolute discrimination is recognition of not-self by immune T Cells. We show
Altan-Bonnet, Grégoire, François, Paul
core   +2 more sources

Individual cell sorting. [PDF]

open access: yesJournal of Histochemistry & Cytochemistry, 1979
Current cell sorting machines do not preserve the individual identity of processed cells; after analysis, the cells are assigned to a subpopulation where they are pooled with other similar cells. This paper reports progress on a system that sorts cells individually to precise locations on a microscope slide and preserves them for further observation ...
R T, Stovel, R G, Sweet
openaire   +2 more sources

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