Results 21 to 30 of about 591,980 (296)

A linear B-cell epitope close to the furin cleavage site within the S1 domain of SARS-CoV-2 Spike protein discriminates the humoral immune response of nucleic acid- and protein-based vaccine cohorts

open access: yesFrontiers in Immunology, 2023
BackgroundUnderstanding the humoral immune response towards viral infection and vaccination is instrumental in developing therapeutic tools to fight and restrict the viral spread of global pandemics. Of particular interest are the specificity and breadth
Peter Lorenz   +5 more
doaj   +1 more source

Single-dose SARS-CoV-2 vaccinations with either BNT162b2 or AZD1222 induce disparate Th1 responses and IgA production

open access: yesBMC Medicine, 2022
Background While vaccination programs against the severe acute respiratory syndrome virus 2 (SARS-CoV-2) are globally ongoing, disparate strategies for the deployment of spike antigen show varying effectiveness.
Michael Müller   +6 more
doaj   +1 more source

Infection With Clostridioides difficile Attenuated Collagen-Induced Arthritis in Mice and Involved Mesenteric Treg and Th2 Polarization

open access: yesFrontiers in Immunology, 2020
ObjectivesRheumatoid arthritis is an autoimmune disease with multifactorial etiopathogenesis. Among the environmental factors, mucosal infections and the inducing pathobionts are gaining increasing attention. We here set out to explore the gut-joint-axis
Christian Johann Schmidt   +10 more
doaj   +1 more source

Individually or as a Team—The Immunological Milieu in the Lung Caused by Migrating Single-Sex or Mixed-Sex Larvae of Schistosoma mansoni

open access: yesPathogens, 2023
While the lung is considered an efficient site for stopping the larvae of the acute Schistosoma spp. infection phase from migrating through extensive inflammatory responses in the surrounding tissues, little is known about these processes.
Miriam Bischofsberger   +8 more
doaj   +1 more source

Dynamics of Antibacterial Drone Establishment in Staphylococcus aureus: Unexpected Effects of Antibiotic Resistance Genes

open access: yesmBio, 2021
The antibacterial drone (ABD) system is based on repurposing the phage-inducible staphylococcal pathogenicity islands (SaPIs) for use as antibacterial agents that are indifferent to antibiotic resistance.
Neha Dhasmana   +6 more
doaj   +1 more source

Using neural networks for high-speed blood cell classification in a holographic-microscopy flow-cytometry system [PDF]

open access: yes, 2015
High-throughput cell sorting with flow cytometers is an important tool in modern clinical cell studies. Most cytometers use biomarkers that selectively bind to the cell, but induce significant changes in morphology and inner cell processes leading ...
Bienstman, Peter   +4 more
core   +2 more sources

Single-cell genomics based on Raman sorting reveals novel carotenoid-containing bacteria in the Red Sea [PDF]

open access: yes, 2016
Cell sorting coupled with single-cell genomics is a powerful tool to circumvent cultivation of microorganisms and reveal microbial ‘dark matter’. Single-cell Raman spectra (SCRSs) are label-free biochemical ‘fingerprints’ of individual cells, which can ...
Davison, Paul A.   +11 more
core   +4 more sources

Cell Separations and Sorting [PDF]

open access: yesAnalytical Chemistry, 2019
This document is the Accepted Manuscript version of a Published Work that appeared in final form in Analytical Chemistry, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/acs.analchem.9b05357. ; NIBIB Grant P41-EB020594 ; COBRE Grant
Malgorzata A. Witek   +2 more
openaire   +3 more sources

Cell Sorting daring Pattern Formation in Dictyostelium [PDF]

open access: yes, 1981
Formation of the prestalk-prespore pattern in Dictyostelium was investigated in slugs and submerged clumps of cells. Prestalk and prespore cells were identified by staining with vital dyes, which are shown to be stable cell markers.
David, Charles N., Sternfeld, John
core   +1 more source

Extremely High-Throughput Parallel Microfluidic Vortex-Actuated Cell Sorting

open access: yesMicromachines, 2021
We demonstrate extremely high-throughput microfluidic cell sorting by making a parallel version of the vortex-actuated cell sorter (VACS). The set-up includes a parallel microfluidic sorter chip and parallel cytometry instrumentation: optics, electronics
Alex A. Zhukov   +8 more
doaj   +1 more source

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