Results 11 to 20 of about 591,980 (296)

Intelligent Image-Activated Cell Sorting [PDF]

Cell, 2018
A fundamental challenge of biology is to understand the vast heterogeneity of cells, particularly how cellular composition, structure, and morphology are linked to cellular physiology. Unfortunately, conventional technologies are limited in uncovering these relations.
Nitta, Nao, Sugimura, Takeaki, Isozaki, Akihiro, Mikami, Hideharu, Hiraki, Kei, Sakuma, Shinya, Iino, Takanori, Arai, Fumihito, Endo, Taichiro, Fujiwaki, Yasuhiro, Fukuzawa, Hideya, Hase, Misa, Hayakawa, Takeshi, Hiramatsu, Kotaro, Hoshino, Yu, Inaba, Mary, Ito, Takuro, Karakawa, Hiroshi, Kasai, Yusuke, Koizumi, Kenichi, Lee, SangWook, Lei, Cheng, Li, Ming, Maeno, Takanori, Matsusaka, Satoshi, Murakami, Daichi, Nakagawa, Atsuhiro, Oguchi, Yusuke, Oikawa, Minoru, Ota, Tadataka, Shiba, Kiyotaka, Shintaku, Hirofumi, Shirasaki, Yoshitaka, Suga, Kanako, Suzuki, Yuta, Suzuki, Nobutake, Tanaka, Yo, Tezuka, Hiroshi, Toyokawa, Chihana, Yalikun, Yaxiaer, Yamada, Makoto, Yamagishi, Mai, Yamano, Takashi, Yasumoto, Atsushi, Yatomi, Yutaka, Yazawa, Masayuki, Di Carlo, Dino, Hosokawa, Yoichiroh, Uemura, Sotaro, Ozeki, Yasuyuki, Goda, Keisuke   +50 more
openaire   +4 more sources

Degenerative Joint Damage Is Not a Risk Factor for Streptococcal Sepsis and Septic Arthritis in Mice

Life, 2021
Septic arthritis (SA) is an aggressive joint disorder causing invalidity and mortality. Although epidemiological studies suggest osteoarthritis (OA) as a risk factor for SA, experimental insights into the relatedness of both diseases are lacking.
Johann Volzke, Brigitte Müller-Hilke
doaj   +1 more source

Vaccine-Induced T-Cell and Antibody Responses at 12 Months after Full Vaccination Differ with Respect to Omicron Recognition

Vaccines, 2022
More than a year after the first vaccines against the novel SARS-CoV-2 were approved, many questions still remain about the long-term protection conferred by each vaccine.
Franz Mai, Johann Volzke, Emil C. Reisinger, Brigitte Müller-Hilke   +3 more
doaj   +1 more source

Distinguishing Incubation and Acute Disease Stages of Mild-to-Moderate COVID-19

Viruses, 2022
While numerous studies have already compared the immune responses against SARS-CoV-2 in severely and mild-to-moderately ill COVID-19 patients, longitudinal trajectories are still scarce.
Michael Müller, Johann Volzke, Behnam Subin, Christian Johann Schmidt, Hilte Geerdes-Fenge, Emil Christian Reisinger, Brigitte Müller-Hilke   +6 more
doaj   +1 more source

Mindfulness-based intervention helps preclinical medical students to contain stress, maintain mindfulness and improve academic success

BMC Medical Education, 2021
Background Stress among students is on the rise during early medical school and has been implicated in poor academic performance. Several methods are being discussed to efficiently reduce stress, among them mindfulness-based interventions.
Luisa Charlotte Lampe, Brigitte Müller-Hilke   +1 more
doaj   +1 more source

Prolonged treadmill training is not able to prevent ovariectomy-induced bone loss

Frontiers in Physiology, 2022
Introduction: Exercise is widely recognized as prophylaxis for osteoporosis. However, exactly which type of exercise is best to prevent loss of bone mass remains undefined.
Tim Massing, Tim Massing, Konstantin Will, Konstantin Will, Michael Müller, Johann Aleith, Tobias Lindner, Mareike Warkentin, Brigitte Müller-Hilke, Thomas Mittlmeier   +9 more
doaj   +1 more source

Intuitive, Image-Based Cell Sorting Using Optofluidic Cell Sorting [PDF]

Analytical Chemistry, 2007
We present a microfluidic cell-sorting device which augments microscopy with the capability to perform facile image-based cell sorting. This combination enables intuitive, complex phenotype sorting based on spatio-temporal fluorescence or cell morphology.
J R, Kovac, J, Voldman
openaire   +2 more sources

Inflammatory Joint Disease Is a Risk Factor for Streptococcal Sepsis and Septic Arthritis in Mice

Frontiers in Immunology, 2020
Septic arthritis is a medical emergency associated with high morbidity and mortality, yet hardly any novel advances exist for its clinical management.
Johann Volzke, Daniel Schultz, Marcel Kordt, Michael Müller, Wendy Bergmann, Karen Methling, Bernd Kreikemeyer, Brigitte Müller-Hilke, KoInfekt Study Group   +8 more
doaj   +1 more source

CAMT-MPL: congenital amegakaryocytic thrombocytopenia caused by MPL mutations - heterogeneity of a monogenic disorder - a comprehensive analysis of 56 patients

Haematologica, 2020
Congenital amegakaryocytic thrombocytopenia caused by deleterious homozygous or compound heterozygous mutations in MPL (CAMT-MPL) is a rare inherited bone marrow failure syndrome presenting as an isolated thrombocytopenia at birth progressing to ...
Manuela Germeshausen, Matthias Ballmaier
doaj   +1 more source

A pipeline for targeted metagenomics of environmental bacteria. [PDF]

, 2020
BackgroundMetagenomics and single cell genomics provide a window into the genetic repertoire of yet uncultivated microorganisms, but both methods are usually taxonomically untargeted.
Bowers, Robert M, Fuchs, Bernhard M, Goudeau, Danielle, Grieb, Anissa, Lee, Janey, Malmstrom, Rex R, Oggerin, Monike, Woyke, Tanja   +7 more
core   +2 more sources