Results 11 to 20 of about 564,510 (265)

Rapidly rendering cells phagocytic through a cell surface display technique and concurrent Rac activation [PDF]

open access: greenScience Signaling, 2014
A method to enforce the cell surface display of molecules of interest can change cellular function.
Hiroki, Onuma   +7 more
openaire   +3 more sources

Novel Properties for Endoglucanase Acquired by Cell-Surface Display Technique

open access: closedJournal of Microbiology and Biotechnology, 2015
In order to improve the stability of endoglucanase under thermal and acidic conditions, the endoglucanase gene was fused to the N-terminus of the Saccharomyces cerevisiae pir gene, encoding the cell wall protein PIR. The fusion gene was transformed into Pichia pastoris GS115 for expression.
Baosheng, Shi   +5 more
openaire   +3 more sources

Developing and characterizing a single-domain antibody (nanobody) against human cytotoxic T-lymphocyte-associated protein 4 (hCTLA-4) [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2021
Objective(s): Cytotoxic T-lymphocyte-associated protein-4 (CTLA-4) is the most important human immune checkpoint that modulates T cells activity and brings about immune-homeostasis.
Nazli Sotoudeh   +4 more
doaj   +1 more source

Strategies to Screen Anti-AQP4 Antibodies from Yeast Surface Display Libraries

open access: yesAntibodies, 2022
A rapid and effective method to identify disease-specific antibodies from clinical patients is important for understanding autoimmune diseases and for the development of effective disease therapies.
Aric Huang   +11 more
doaj   +1 more source

A dual-mode surface display system for the maturation and production of monoclonal antibodies in glyco-engineered Pichia pastoris. [PDF]

open access: yesPLoS ONE, 2013
State-of-the-art monoclonal antibody (mAb) discovery methods that utilize surface display techniques in prokaryotic and eukaryotic cells require multiple steps of reformatting and switching of hosts to transition from display to expression.
Hussam H Shaheen   +8 more
doaj   +1 more source

Yeast Surface Display Platform for Rapid Selection of an Antibody Library via Sequential Counter Antigen Flow Cytometry

open access: yesAntibodies, 2022
Yeast surface display techniques have been increasingly employed as a tool for both the discovery and affinity maturation of antibodies. In this study, we describe the use of yeast surface display for the selection and affinity maturation of antibodies ...
Bhupal Ban   +2 more
doaj   +1 more source

Surface functionalization of core-shell QDs for solar photovoltaic and anti-cancer applications

open access: yesApplied Surface Science Advances, 2021
We undertook this present study; a simple and straight forward approach is developed to achieve CdSe/ZnS core-shell quantum dots by hydrothermal method and change the different hydrazine hydrate concentrations.
B. Arjun Kumar   +6 more
doaj   +1 more source

Selection of novel human scFvs against cancer antigen IL1RAP by phage and yeast surface display technology

open access: yesBiotechnology & Biotechnological Equipment, 2020
The objective of this study was isolation of humanized single-chain variable fragment (scFv) antibodies against IL1RAP, a promising cancer marker in leukemia and other tumors.
Shixin Duan   +5 more
doaj   +1 more source

Exosomes and Extracellular Vesicles as Emerging Theranostic Platforms in Cancer Research

open access: yesCells, 2020
Exosomes are endosome-derived nanovesicles produced by healthy as well as diseased cells. Their proteic, lipidic and nucleic acid composition is related to the cell of origin, and by vehiculating bioactive molecules they are involved in cell-to-cell ...
Giorgia Ailuno   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy