Results 21 to 30 of about 564,510 (265)

Protein Engineering and High‐Throughput Screening by Yeast Surface Display: Survey of Current Methods

Small Science, 2023
Yeast surface display (YSD) is a powerful tool in biotechnology that links genotype to phenotype. In this review, the latest advancements in protein engineering and high‐throughput screening based on YSD are covered.
Joanan Lopez-Morales, Rosario Vanella, Elizabeth A. Appelt, Sarah Whillock, Alexandra M. Paulk, Eric V. Shusta, Benjamin J. Hackel, Chang C. Liu, Michael A. Nash   +8 more
doaj   +1 more source

Anchoring of proteins to lactic acid bacteria [PDF]

, 1999
The anchoring of proteins to the cell surface of lactic acid bacteria (LAB) using genetic techniques is an exciting and emerging research area that holds great promise for a wide variety of biotechnological applications. This paper reviews five different
A Hoick, A Mercenier, A Robert, A Strauss, A Strauss, AJ Haandrikman, AP Pugsley, C Andréoni, CBM Maassen, CM Franke, CM Franke, CM Rush, D Medaglini, D Medaglini, D Medaglini, E Gunneriusson, FO Eko, G Buist, G Buist, G Georgiou, G Pozzi, G Pozzi, G Pozzi, G Pozzi, G Pozzi, G Vidgrén, H Ton-That, H Ton-That, HJ Boot, I Poquet, J Kok, JC Piard, JM Wells, K Robinson, L Steidler, M, M Hansson, M Hofnung, ML Callegari, MR Oggioni, MR Oggioni, O Schneewind, O Schneewind, O Schneewind, P Samuelson, P Vos, PH Pouwels, PH Pouwels, PM Norton, PM Norton, RJ Leer, S Fabio, S Liljeqvist, S Ricci, S Stahl, S Tynkkynen, SC Cebolla, T Toba, TN Nguyen, TN Nguyen, UB Sleytr, VA Fischetti, VA Fischetti, VA Fischetti, WW Navarre, WW Navarre, WW Navarre   +66 more
core   +1 more source

Drug-like antibodies with high affinity, diversity and developability directly from next-generation antibody libraries

mAbs, 2021
Therapeutic antibodies must have “drug-like” properties. These include high affinity and specificity for the intended target, biological activity, and additional characteristics now known as “developability properties”: long-term stability and resistance
Andre Azevedo Reis Teixeira, Michael Frank Erasmus, Sara D’Angelo, Leslie Naranjo, Fortunato Ferrara, Camila Leal-Lopes, Oliver Durrant, Cecile Galmiche, Aleardo Morelli, Anthony Scott-Tucker, Andrew Raymon Morton Bradbury   +10 more
doaj   +1 more source

VAN LCOS microdisplays: a decade of technological evolution [PDF]

, 2011
—Microdisplays of the liquid crystals on silicon (LCOS) type have gone through a rapid evolution during the last decade. We present an overview of how vertically aligned nematic (VAN) LCOS have evolved from an attractive, but notoriously difficult and ...
Cuypers, Dieter, De Smet, Herbert, Van Calster, André   +2 more
core   +1 more source

Selection of binding targets in parasites using phage-display and aptamer libraries in vivo and in vitro

Frontiers in Immunology, 2013
Parasite infections are largely dependent on interactions between pathogen and different host cell populations to guarantee a successful infectious process.
Renata Rosito Tonelli, Walter eColli, Maria Júlia Manso Alves   +2 more
doaj   +1 more source

Evolutionarily unique mechanistic framework of clathrin-mediated endocytosis in plants

eLife, 2020
In plants, clathrin mediated endocytosis (CME) represents the major route for cargo internalisation from the cell surface. It has been assumed to operate in an evolutionary conserved manner as in yeast and animals.
Madhumitha Narasimhan, Alexander Johnson, Roshan Prizak, Walter Anton Kaufmann, Shutang Tan, Barbara Casillas-Pérez, Jiří Friml   +6 more
doaj   +1 more source

Nanoscale integration of single cell biologics discovery processes using optofluidic manipulation and monitoring. [PDF]

, 2019
The new and rapid advancement in the complexity of biologics drug discovery has been driven by a deeper understanding of biological systems combined with innovative new therapeutic modalities, paving the way to breakthrough therapies for previously ...
Chen, Ching, Chen, Irwin, Chong, Su, Hamburger, Agi, Jess, Philip, Jorgolli, Marsela, Le, Kim, Lin, Fen-Fen, Miranda, Les P, Mock, Marissa, Munro, Trent, Nevill, Tanner, Stevens, Jennitte, Tagari, Philip, Tan, Christopher, Winters, Aaron, Wu, Ming, Xu, Han   +17 more
core   +1 more source

Surface display of Salmonella epitopes in Escherichia coli and Staphylococcus carnosus

Microbial Cell Factories, 2011
Background Salmonella enterica serotype Enteritidis (SE) is considered to be one of the most potent pathogenic Salmonella serotypes causing food-borne disease in humans.
Hai Truong, Gustavsson Martin, de Valdivia Ernesto, Nhan Nguyen, Larsson Gen   +4 more
doaj   +1 more source

Antibacterial and Anti-Inflammatory Effects of Apolipoprotein E

Biomedicines, 2022
Apolipoprotein E (APOE) is a lipid-transport protein that functions as a key mediator of lipid transport and cholesterol metabolism. Recent studies have shown that peptides derived from human APOE display anti-inflammatory and antimicrobial effects. Here,
Manoj Puthia, Jan K. Marzinek, Ganna Petruk, Gizem Ertürk Bergdahl, Peter J. Bond, Jitka Petrlova   +5 more
doaj   +1 more source

A contact lens with built-in display: science fiction or not? [PDF]

, 2013
Recent progress in microsystems integration technology such as ultra-thin chip packaging, stretchable interconnections, thin-film batteries and organic photovoltaics makes it feasible to incorporate various electronic components and transducers in ...
Cuypers, Dieter, De Smet, Herbert, De Smet, Jelle, Joshi, Pankaj, Weng, Ching-Pao   +4 more
core   +1 more source