Results 21 to 30 of about 514,364 (216)

Epitope mapping using mRNA display and a unidirectional nested deletion library [PDF]

, 2005
In vitro selection targeting an anti-polyhistidine monoclonal antibody was performed using mRNA display with a random, unconstrained 27-mer peptide library.
Ja, William W., Olsen, Brett N., Roberts, Richard W.   +2 more
core   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Messy Tabletops: Clearing Up The Occlusion Problem [PDF]

, 2013
When introducing interactive tabletops into the home and office, lack of space will often mean that these devices play two roles: interactive display and a place for putting things.
Brewster, Stephen, Freeman, Euan
core  

Identification of novel small molecule inhibitors of ETS transcription factors

FEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla, Zary Forghany, Jin Ma, Johan G. Hollander, Ruta Nachane, Karoly Szuhai, Pancras C. W. Hogendoorn, Peter ten Dijke, Dipen Shah, David A. Baker   +9 more
wiley   +1 more source

miRNA‐29 regulates epidermal and mesenchymal functions in skin repair

FEBS Letters, EarlyView.
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan, Rosa Sanchez‐Alvarez, Chiho Kambara, Poojitha Rajasekar, Yuluang Wang, François Halloy, Jonathan Hall, Hans‐Jürgen Stark, Iris Martin, Petra Boukamp, Svitlana Kurinna   +10 more
wiley   +1 more source

Shipboard Techniques for Oceanographic Observations [PDF]

, 1995
This report gives the details of water sampling methods and chemical analyses used during MLML participation in the EOS MODIS investigations. It is intended to be used as a reference manual for those engaged in shipboard work.
Broenkow, William W., Feinholz, Michael, E., Flora, Stephanie J., Gashler, J. Andrew   +3 more
core  

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Label-free segmentation of co-cultured cells on a nanotopographical gradient [PDF]

, 2013
The function and fate of cells is influenced by many different factors, one of which is surface topography of the support culture substrate. Systematic studies of nanotopography and cell response have typically been limited to single cell types and a ...
Alberts B., Anderson D. G., Anderson D. G., Bakker R. M., Boss J., Cardona A., Cho B. H., Csaderova L., Curtis A. S. G., Dalby M. J., Dalby M. J., De Mel A., Ding Y., Gadegaard N., Gadegaard N., Gallant N. D., Geysen H. M., Glassford S., John Stormonth-Darling, Jones T. R., Jones T. R., Kamentsky L., Khetani S. R., Kirkpatrick C. J., Kolind K., Kunzler T. P., Mathis O. Riehle, Matthew J. Dalby, Ngo J. T., Nikolaj Gadegaard, Paul M. Reynolds, Pedersen R. H., Rasmus H. Pedersen, Reynolds P. M., Rivera Gil P., Schift H., Simon C. G., Stormonth-Darling J. M., Unadkat H. V, Vickaryous M. K., Yang J., Zelzer M.   +41 more
core   +1 more source

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

FEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek, Ariane Fischer, Mariano Ruz Jurado, Anita Tamiato, Tara Procida‐Kowalski, Jochen Wilhelm, Dennis Hecker, Maximilian Merten, Felicitas Escher, Badder Kattih, Valentina Puntmann, David John, Marcel H. Schulz, Eike Nagel, Stefanie Dimmeler, Guillermo Luxán   +15 more
wiley   +1 more source

Emerging Next Generation Solar Cells Route to High Efficiency and Low Cost [PDF]

, 2017
Generation of clean energy is one of the main challenges of the 21st century. Solar energy is the most abundantly available renewable energy source which would be supplying more than 50 of the global electricity demand in 2100.
Mahmood, Dr Zahid Hasan, Rashid, Dr M. Junaebur, Sadek, Md Samiul Islam   +2 more
core   +1 more source