Results 281 to 290 of about 3,396,679 (311)

Non canonical BRCA1 promotes cell survival via modulating PARP13-mediated SEC61G mRNA decay. [PDF]

open access: yesOncogenesis
Sun B   +8 more
europepmc   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

open access: yesFEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee   +3 more
wiley   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

open access: yesFEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez   +5 more
wiley   +1 more source

Correction to: The receptor for advanced glycation end products (RAGE) sustains autophagy and limits apoptosis, promoting pancreatic tumor cell survival. [PDF]

open access: yesCell Death Differ
Kang R   +8 more
europepmc   +1 more source

Sustained Neurotrophic Factor Co-Treatment Enhances Donor and Host Retinal Ganglion Cell Survival in Mice. [PDF]

open access: yesTransl Vis Sci Technol
Soucy JR   +6 more
europepmc   +1 more source

NaCl and urea modulate CD8+ T cell survival, renal accumulation, and response to BK virus. [PDF]

open access: yesJCI Insight
Falahat P   +12 more
europepmc   +1 more source

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