Results 271 to 280 of about 8,088,933 (310)
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Current Opinion in Immunology, 1999
T cell survival in the periphery is an active process, depending on continuous TCR engagement by peptide-MHC complexes and/or response to environmental cytokines. Naive T cells require interactions with the MHC restricting element. The survival requirements of memory T cells are as yet insufficiently characterized, but MHC-restricted interactions are ...
Freitas, A. A., Rocha, B.
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T cell survival in the periphery is an active process, depending on continuous TCR engagement by peptide-MHC complexes and/or response to environmental cytokines. Naive T cells require interactions with the MHC restricting element. The survival requirements of memory T cells are as yet insufficiently characterized, but MHC-restricted interactions are ...
Freitas, A. A., Rocha, B.
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Mast Cell Apoptosis and Survival
2011Mast cells are enigmatic cells that are recognized as critical components of our immune system. They are strategically localized at the host/environment interface, display a long lifespan once situated in tissues and have the ability to produce, store and upon activation, release immuno-regulatory molecules.
Maria, Ekoff, Gunnar, Nilsson
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Survival in Granular Cell Astrocytomas
Journal of Neurological Surgery Part A: Central European Neurosurgery, 2014Granular cell astrocytomas (GCAs) are rarely encountered aggressive glial neoplasms. Treatment options comprise surgery, radiotherapy, and chemotherapy. Due to the small number of cases, a standard therapeutic regimen for GCA does not exist.We report on the case of a 64-year-old woman with GCA subjected to tumor biopsy followed by radiochemotherapy ...
Benjamin, Voellger +6 more
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Red cell survival in the puerperium
American Journal of Obstetrics and Gynecology, 1968Abstract Red cell survival was measured in 10 normal puerperal women using radioactive chromium tagging of red cells. The T 1/2 varied between 21 and 33 days as compared with 22 to 37 days in 12 normal nonpregnant subjects. The data indicate that red cell survival in the puerperium is normal.
N K, De Leeuw +3 more
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Repair processes and cell survival
The British Journal of Radiology, 1972Abstract A model of cell survival after irradiation is presented which explicitly incorporates a repair process. The model is based on Powers' suggestion of a “pool”, and is developed along the lines initiated by Lajtha and Oliver (1961). The repair process corresponding to the shoulder on the survival curve is distinguished from the process ...
J, Laurie, J S, Orr, C J, Foster
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Preconditioning and Stem Cell Survival
Journal of Cardiovascular Translational Research, 2009The harsh ischemic and cytokine-rich microenvironment in the infarcted myocardium, infiltrated by the inflammatory and immune cells, offers a significant challenge to the transplanted donor stem cells. Massive cell death occurs during transplantation as well as following engraftment which significantly lowers the effectiveness of the heart cell therapy.
Husnain Kh, Haider, Muhammad, Ashraf
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Annals of the New York Academy of Sciences, 2009
One of the central issues in neuroscience today is the study of the mechanisms of neuronal survival. Since the discovery of nerve growth factor (almost 60 years ago), many groups have clearly demonstrated the central role of neurotrophins on the regulation of neuronal cell survival during developmental stages as well as during adult life.
Elizabeth Giestal, de Araujo +2 more
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One of the central issues in neuroscience today is the study of the mechanisms of neuronal survival. Since the discovery of nerve growth factor (almost 60 years ago), many groups have clearly demonstrated the central role of neurotrophins on the regulation of neuronal cell survival during developmental stages as well as during adult life.
Elizabeth Giestal, de Araujo +2 more
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Neuroglobin and neuronal cell survival
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2013The balance between neuronal apoptosis and survival sculpts the developing brain and has an important role in neurodegenerative diseases. Thus, the individuation of signals that could modulate the cell death machinery as well as enhance survival in neurons promises to provide multiple points of therapeutic intervention in neurodegenerative diseases ...
Fiocchetti M. +3 more
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Cytokine-Mediated Cell Survival
International Journal of Hematology, 2004Pathways through which signals emanating from cytokine receptors support cell survival have long been a focus of intensive research. For Baf-3, a murine interleukin 3-dependent cell line, the 2 distinct pathways involved are JAK/STATs/Bcl-xL and Ras/PI3-K.
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Autophagy—Cell Survival and Death
2019Autophagy, which is one of the most important ways to maintain cell homeostasis plays an important regulatory role in cell survival and death. Currently, it is agreed that autophagy promotes or inhibits cell death depending on the internal and external environment and cell type.
Xiaojie, Yan, Ruimin, Zhou, Zhenyi, Ma
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