Results 271 to 280 of about 2,251,671 (317)
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Clonogenic Cell Survival Assay
2005The clonogenic cell survival assay determines the ability of a cell to proliferate indefinitely, thereby retaining its reproductive ability to form a large colony or a clone. This cell is then said to be clonogenic. A cell survival curve is therefore defined as a relationship between the dose of the agent used to produce an insult and the fraction of ...
Anupama, Munshi +2 more
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Cell Survival and Plating Efficiency
Radiation Research, 1987The question of whether cellular radiation sensitivity is independent or related to plating efficiency (PE) is addressed. Three different cell lines, one human and mortal (AG 1522), one rodent and immortal (CHO AA8), and one rodent and mortal (C3H 10T1/2), were investigated. The first two showed a strong correlation between radiation sensitivity and PE,
D J, Brenner +3 more
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Preconditioning and Stem Cell Survival
Journal of Cardiovascular Translational Research, 2009The harsh ischemic and cytokine-rich microenvironment in the infarcted myocardium, infiltrated by the inflammatory and immune cells, offers a significant challenge to the transplanted donor stem cells. Massive cell death occurs during transplantation as well as following engraftment which significantly lowers the effectiveness of the heart cell therapy.
Husnain Kh, Haider, Muhammad, Ashraf
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Involvement of integrins in cell survival
Cancer and Metastasis Reviews, 1995Apoptosis is a regulated process of cell death by which cells actively participate in their own destruction. In multicellular organisms, the balance between cell proliferation and apoptosis provides homeostatic control, and a regulatory failure of either event can contribute to oncogenesis.
R C, Bates, L F, Lincz, G F, Burns
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Red cell survival in galactosemia
The Journal of Pediatrics, 1966Erythrocyte survival in a 4 1/2-year-old galactosemic patient was studied. In vitroautohemolysis of the patient's red cells was within normal limits in both the absence and presence of galactose. The half-lives of Cr 51 -tagged cells in the patient's circulation while he was on a milk-free diet and in the father's circulation while he was on an ...
M Y, Wang, J F, Desforges
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2002
The development of assays for measuring the survival of individual tumor cells revolutionized the study of experimental cancer therapy by enabling researchers to move from assessing the gross responses of tumors to measuring the survival of cells in the critical, clonogenic tumor-cell populations (1).
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The development of assays for measuring the survival of individual tumor cells revolutionized the study of experimental cancer therapy by enabling researchers to move from assessing the gross responses of tumors to measuring the survival of cells in the critical, clonogenic tumor-cell populations (1).
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Autophagy—Cell Survival and Death
2019Autophagy, which is one of the most important ways to maintain cell homeostasis plays an important regulatory role in cell survival and death. Currently, it is agreed that autophagy promotes or inhibits cell death depending on the internal and external environment and cell type.
Xiaojie, Yan, Ruimin, Zhou, Zhenyi, Ma
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Plasma cell development and survival
Immunological Reviews, 2010Summary: Plasma cells have long been recognized as the basis of humoral immunity, yet we are only now beginning to appreciate the complexities of plasma cell development and the fact that not all plasma cells are created equal. In vivo, plasma cells can arise from two developmental routes: one occurring outside the follicle and another within the ...
Sarah A, Oracki +4 more
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A molecular theory of cell survival
Physics in Medicine & Biology, 1973A theory is presented to explain the effect of radiation on cell survival. The theory is based on the assumption that a double strand break in the DXA helix is the critical damage. The theory is derived from the radiation induced molecular bond breaks in the DNA strands and parameters are included to take account of various repair processes which may ...
K H, Chadwick, H P, Leenhouts
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Current Opinion in Immunology, 1999
T cell survival in the periphery is an active process, depending on continuous TCR engagement by peptide-MHC complexes and/or response to environmental cytokines. Naive T cells require interactions with the MHC restricting element. The survival requirements of memory T cells are as yet insufficiently characterized, but MHC-restricted interactions are ...
Freitas, A. A., Rocha, B.
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T cell survival in the periphery is an active process, depending on continuous TCR engagement by peptide-MHC complexes and/or response to environmental cytokines. Naive T cells require interactions with the MHC restricting element. The survival requirements of memory T cells are as yet insufficiently characterized, but MHC-restricted interactions are ...
Freitas, A. A., Rocha, B.
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