Transformation From Oxyntic Gland Neoplasm Into Advanced Gastric Cancer via <i>TP53</i> Mutation: A First Case Report. [PDF]
Komatsu A +8 more
europepmc +1 more source
Relocalization of cell adhesion molecules during neoplastic transformation of human fibroblasts.
Studying neoplastic transformation of telomerase immortalized human fibroblasts (cen3tel), we found that the transition from normal to tumorigenic cells was associated with the loss of growth contact inhibition, the acquisition of an epithelial-like ...
Belgiovine C, Mondello C, Chiodi I
core
Genetic variants of EcPV2 E6 and E7 in equine genital and oronasal squamous cell carcinoma
Abstract Background Since its discovery in 2008, equine papillomavirus type 2 (EcPV2) has been detected in up to 100% of equine genital and up to 40% of equine oronasal squamous cell carcinomas (SCCs). Preliminary sequence data point to the existence of EcPV2 E6 and E7 oncogene variants compared to the British reference sequence from 2008.
Maya Jenner, Sabine Brandt
wiley +1 more source
Exophytic Papillary Thyroid Carcinoma With Anaplastic Transformation in a Cervical Lymph Node: A Case Report and Review of the Literature. [PDF]
Garcia Avilán I +4 more
europepmc +1 more source
Abstract Early diagnosis of hepatocellular carcinoma (HCC) remains challenging because conventional serum biomarkers, especially alpha‐fetoprotein (AFP), show limited sensitivity for early‐stage disease. Recent progress in engineered molecular diagnostics provides new opportunities to improve HCC detection through integrated material, molecular, and ...
Jingzhi Xue +5 more
wiley +1 more source
HPV-Associated Field Cancerization: Molecular Alterations in Histologically Normal Tissues and Implications for Early Detection and Cancer Prevention. [PDF]
Demir A +4 more
europepmc +1 more source
Null Effects of the State Pension Age on Mortality in the Netherlands
ABSTRACT Increasing the state pension (SP) age in the Netherlands from 65 years in 2012 to 67 in 2024 has been shown to cause individuals to work longer. This study addresses a concern regarding possible adverse health effects of an increased SP‐age, for example, because individuals trade health investments for working time. We empirically investigated
Adriaan Kalwij, Arie Kapteyn
wiley +1 more source
Spermatocytic Tumor Arising in a Cryptorchid Testis: A Case Report and Narrative Review. [PDF]
Barbu LA +9 more
europepmc +1 more source
Thyroid cell transformation requires the expression of the HMGA1 proteins.
Elevated expression of HMGA1 and HMGA2 proteins is correlated with a highly malignant phenotype in several human tumors. We previously demonstrated that the block of HMGA2 protein synthesis prevented rat thyroid cell transformation by murine retroviruses.
Pierantoni GM +4 more
core
ABSTRACT Background Frailty and sarcopenia may influence head and neck cancer (HNC) treatment outcomes, including dysphagia. Current understanding of this relationship, however, remains limited. This scoping review aimed to synthesize existing evidence on the relationship between frailty and/or sarcopenia and dysphagia in adults with HNC.
Rishni Perera +4 more
wiley +1 more source

