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Viral-inhibiting factor in polyoma-transformed cells I. Evidence from cell fusion
Virology, 1977Abstract A factor inhibiting the replication of polyoma (Py) virus, present in cells transformed by this virus, was evidenced by fusion techniques. The mouse parental kidney cells were infected with Py virus prior to fusion, and fused, either with normal or Py virus-transformed hamster or mouse cells.
M, Berebbi +3 more
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Stability of p53 protein in rat cells transformed by various viral transforming genes
Virology, 1992To clarify the correlation between metabolic stabilization of p53 protein and cellular transformation, we transformed the normal rat cell line F2408 with various viral transforming genes and examined the expression and stability of p53 protein in these transformed cells by pulse-chase immunoprecipitation experiments.
H, Inoue +3 more
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Further study of β‐tgfs released by virally transformed and non‐transformed cells
International Journal of Cancer, 1985AbstractChicken embryo fibroblasts sensitized by ts RSV respond to TGFs present in the media of non‐transformed FR3T3 and NRK‐4 rat cells and of the same cells transformed by KiMSV or RSV. They also respond to TGFs present in the media of BHK hamster cells transformed by MoMSV, PyV or RSV.
C, Krycève-Martinerie +4 more
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State of viral DNA in BK virus-transformed rabbit cells
Virology, 1980Abstract Semipermissive rabbit liver, brain, and kidney cells were transformed by BK virus (BKV). All cells of the three resulting cell lines produced BKV T antigen. Viral DNA was detected by DNA-DNA reassociation kinetics and by blot-transfer hybridization.
Chenciner N. +6 more
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Gangliosides of chemically and virally transformed rat embryo cells
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1975The gangliosides of control rat embryo cells, 3-methylcholanthrene, Rauscher leukemia virus, and combined 3-methylcholanthrene-Rauscher leukemia virus transformants were examined using [14 C]glucosamine as a tracer. All four cell lines exhibited a complex pattern of gangliosides.
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Biochemical characteristics of normal and virally transformed mouse cell lines
Journal of Cellular Physiology, 1972AbstractNormal and virally transformed mouse cells respond differently in vitro to high concentrations of potassium. A higher potassium concentration is required to inhibit multiplication of SV40 transformed 3T3 cells to the same extent as that of normal 3T3 cells.
M, Yoshikawa-Fukada, T, Nojima
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Viral messenger RNAs in six lines of adenovirus-transformed cells
Virology, 1981Abstract We have compared the proteins translated in vitro using virus-specific mRNA from six lines of adenovirus-transformed cells (F4, F17, F19, REM, T2C4, and 293) with those made using RNA from productively infected cells. The mRNAs for proteins E1A-58K, 54K, 48K, and 42K, and for E1B-15K, were detected in all cell lines and for E1B-57K in at ...
J B, Lewis, M B, Mathews
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Increased mutation rates in doubly viral transformed Chinese hamster cells
Somatic Cell Genetics, 1979An untransformed parental Chinese hamster cell line, one polyoma transformed clone, and two clones containing both SV40 and polyoma DNA were tested for the appearance of variants resistant to 6-thioguanine or oubain. The frequency of such variants was found to be highest in doubly transformed cells.
S, Goldberg, V, Defendi
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Viral RNA Subunits in Cells Transformed by RNA Tumor Viruses
Science, 1972Single-stranded 35 S and 20 S viral RNA species are synthesized in virus-producing mouse and rat cells transformed by the murine sarcoma virus. A transformed hamster cell line that does not produce virus synthesizes 35 S , but not 20 S viral RNA.
Tsuchida, N, Robin, M S, Green, M
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On the reduced intercellular adhesiveness of virally transformed BHK21 cells
Journal of Cell Science, 1979ABSTRACT Baby hamster kidney fibroblasts (BHK21 cells) transformed by polyoma or Rous sarcoma viruses aggregate less than the untransformed parental cells when incubated in growth medium in a gyratory shaker for 18–24 h. This difference can be measured by electronic particle counting, or by filtering aggregated suspensions of 32 P ...
J G, Edwards +3 more
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