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Transformation of Human Cells by Viral and Cellular Oncogenes
1986Human adenoviruses have been widely used in studies on the expression of genes in eukaryotic cells and in studies of experimentally produced cancer (for reviews see Flint, 1982; Branton et al., 1985; Gallimore et al., 1985a). The oncogenic potential of these viruses was identified by the ability of certain serotypes to induce tumours following ...
Philip J. Byrd, Phillip H. Gallimore
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Epidermal Growth Factors Enhances Viral Transformation of Granulosa Cells
Science, 1981Kirsten sarcoma virus produced a low incidence of transient morphological transformation in primary cultures of rat ovarian granulosa cells. In the presence of epidermal growth factor, the incidence of transient transformation increased severalfold and two continuous cell lines were established.
J, Harrison, N, Auersperg
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Organization and Expression of Viral Genes in Adenovirus-Transformed Cells
1982Publisher Summary This chapter discusses the organization and expression of viral genes in adenovirus-transformed cells. Not all human adenoviruses are tumorigenic when inoculated into newborn rodents. Although adenoviruses display differences in their ability to induce tumors in animals, they transform the cells in culture.
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Thymidylate synthetase of in vitro chemically and virally transformed rat cells
Biochimica et Biophysica Acta (BBA) - Enzymology, 1976Thymidylate synthetase (EC 2.1.1) from in vitro 3-methylcholanthreneor Rauscher leukemia virus-transformed rat embryo cells was studied. The enzyme from control or transformed rat cells exhibited a Km for 2'-deoxyuridylic acid of 4.5 +/- 0.2 muM, but the transformants had a higher level of enzyme activity than did control cells. Titration of the enzyme
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Viral DNA in transformed cells
Journal of Molecular Biology, 1974Phillip A. Sharp +2 more
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Virally transformed cells and cytochalasin B
Experimental Cell Research, 1974A. Hirano, T. Kurimura
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Chemical-Viral Interactions in Cell Transformation
Cancer Investigation, 1983openaire +2 more sources
Viral transformation of chick myogenic cells
Experimental Cell Research, 1979P.S. Moss +3 more
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Viral and host heterogeneity and their effects on the viral life cycle
Nature Reviews Microbiology, 2020Valerie Le Sage +2 more
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