Results 301 to 310 of about 1,789,995 (350)
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Spreading of non-transformed and transformed cells
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 1984Mechanisms of cellular reactions responsible for the spreading of non-transformed cultured tissue cells on the surface of various substrata and relationships of these reactions to the control of cell proliferation are reviewed; the special role of the membrane-cytoskeleton interactions leading to extension and attachment of pseudopods is stressed ...
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Unique transforming gene in carcinogen-transformed mouse cells
Nature, 1981Observations from various biological systems suggest that chemical carcinogens transform cells by causing somatic mutations through interacting with DNA1–5. These observations raise several fundamental questions regarding the nature of the transforming genes that are the target of the carcinogens.
Shilo, B, Weinberg, R A
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Genetic transformation of grapevine cells
Plant Cell Reports, 1989Biovar 1 strains ofAgrobacterium tumefaciens have been used to transform a cell suspension culture ofVitis vinifera cv. Cabernet Sauvignon. Cocultivation of cultures withAgrobacterium strains bearing either the cointegrate pGV3850::1103neo, or the binary vector pGA474-68, each gave rise to kanamycin resistant tissue.
T J, Baribault +2 more
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Viral Transformation of Epithelial Cells
2012Approximately 18% of human cancers have a viral etiology and the majority of these involve transformation of epithelial cells. Viral proteins transform epithelia by inducing alterations in the normal cell growth and differentiation pathways through the targeting of host proteins.
Jennifer A, Regan, Laimonis A, Laimins
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La Revue du praticien, 1996
The use of in vitro cell transformation, as a complement to the direct study of tumors and established tumor cell lines, has enabled the analysis of the contribution of diverse genes to the tumor phenotype. The most recent results have underlined the importance of fundamental mechanisms regulating cell proliferation.
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The use of in vitro cell transformation, as a complement to the direct study of tumors and established tumor cell lines, has enabled the analysis of the contribution of diverse genes to the tumor phenotype. The most recent results have underlined the importance of fundamental mechanisms regulating cell proliferation.
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Mitochondrial transformation of mammalian cells
Nature, 1982Resistance to the antibiotics chloramphenicol (CAPr) and efrapeptin (EFr) in mammalian cells is cytoplasmically inherited1,2. We demonstrate here that purified mitochondria obtained from CAPr and EFr cells are taken up by endocytosis and transfer antibiotic resistance to chloramphenicol-(CAPs) and efrapeptin-(EFs) sensitive cells.
M A, Clark, J W, Shay
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Evaluating virus-transformed cell tumorigenicity
Journal of Virological Methods, 1999The tumorigenicity of adenovirus (Ad) 12-transformed mouse cells was evaluated by analyzing the relationship of tumor cell dose to tumor incidence and tumor latency. The tumor producing dose 50% endpoint values used to define these relationships remained stable during 52 weeks of serial passage in tissue culture and were not determined by low frequency
A M, Lewis +4 more
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1979
A number of cell culture systems have been developed over the past ten years in which normal or non-malignant cells have been changed (‘transformed’) with respect to various test markers, including malignancy in the whole animal, following injection of the cells after exposure in vitro to chemical carcinogens. The prime purpose of these methods was the
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A number of cell culture systems have been developed over the past ten years in which normal or non-malignant cells have been changed (‘transformed’) with respect to various test markers, including malignancy in the whole animal, following injection of the cells after exposure in vitro to chemical carcinogens. The prime purpose of these methods was the
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Mutagensis and cell transformation in cell culture
Methods in Cell Science, 1999The current lack of continuous prawn cell lines suitable for the isolation and growth of prawn viruses is a major setback for diagnosis of viral diseases of prawns; isolation and identification of the causative agents are severely hindered and the development of other diagnostic procedures is slowed.
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Reversion in virus-transformed cells
Biochemical Pharmacology, 1971Abstract The hamster cell line BHK21 can be transformed by the Schmidt-Ruppin strain of Rous sarcoma (RSV-SR) and by polyoma viruses. Revertant cells that have apparently lost the virus genes can be obtained in both cases. These occur spontaneously in the case of RSV-SR transformed cells and following the induction of chromosome loss from near ...
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