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Viral Transformation of Epithelial Cells
2012Approximately 18% of human cancers have a viral etiology and the majority of these involve transformation of epithelial cells. Viral proteins transform epithelia by inducing alterations in the normal cell growth and differentiation pathways through the targeting of host proteins.
Jennifer A. Regan, Laimonis A. Laimins
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Physiology of transformed glial cells
Glia, 1995AbstractMuch of our present knowledge of glial cell function stems from studies of glioma cell lines, both rodent (C6, C6 polyploid, and TR33B) and human (1321N1, 138MG, D384, R‐111, T67, Tp‐301MG, Tp‐483MG, Tp‐378MG, U‐118MG, U‐251MG, U‐373MG, U‐787MG, U‐1242MG, and UC‐11MG). New methods such as patch clamp and Ca2+ imaging have lead to rapid progress
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1979
A number of cell culture systems have been developed over the past ten years in which normal or non-malignant cells have been changed (‘transformed’) with respect to various test markers, including malignancy in the whole animal, following injection of the cells after exposure in vitro to chemical carcinogens. The prime purpose of these methods was the
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A number of cell culture systems have been developed over the past ten years in which normal or non-malignant cells have been changed (‘transformed’) with respect to various test markers, including malignancy in the whole animal, following injection of the cells after exposure in vitro to chemical carcinogens. The prime purpose of these methods was the
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1984
Cell transformation assays are presently in wide use in academic, government, and industrial research laboratories and have been applied to studies on the mechanisms of carcinogenesis as well as on the problem of screening chemicals for their carcinogenic potential.
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Cell transformation assays are presently in wide use in academic, government, and industrial research laboratories and have been applied to studies on the mechanisms of carcinogenesis as well as on the problem of screening chemicals for their carcinogenic potential.
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DNA Transformation of Mammalian Cells
2003The manipulation of gene sequences between cells is a fundamental technique in genetics. Mammalian cells will take up and express genes when they are exposed to either metaphase chromosomes or naked genomic or recombinant DNA. In each case the uptake and expression is enhanced by the formation of a DNA-calcium phosphate precipitate (1,2). Alternatively,
Kokila Chotai+3 more
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Endothelial and smooth muscle cell transformation in atherosclerosis
Current Opinion in Lipidology, 2015K. Lao, L. Zeng, Qingbo Xu
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The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation.
Biochimica et Biophysica Acta, 1991P. Angel, M. Karin
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