Results 61 to 70 of about 788,422 (296)

Non-canonical virulence-associated proteins from pathogenic fungi: a review

Academia Molecular Biology and Genomics
Using genomic and proteomic data, many researchers have uncovered novel proteins associated with the cell walls of pathogenic fungi. The literature proposes examples of detected proteins in the cell wall, such as moonlight proteins, with dual ...
José A. Martínez-Álvarez, Naurú Idalia Vargas-Maya, Vianey Olmedo-Monfil, Fátima Berenice Ramírez-Montiel, Felipe Padilla-Vaca, Bernardo Franco   +5 more
doaj   +1 more source

A Glycosylphosphatidylinositol Anchor Is Required for Membrane Localization but Dispensable for Cell Wall Association of Chitin Deacetylase 2 in Cryptococcus neoformans

mBio, 2012
Cell wall proteins (CWPs) mediate important cellular processes in fungi, including adhesion, invasion, biofilm formation, and flocculation. The current model of fungal cell wall organization includes a major class of CWPs covalently bound to β-1,6-glucan
Nicole M. Gilbert, Lorina G. Baker, Charles A. Specht, Jennifer K. Lodge   +3 more
doaj   +1 more source

Proteomic analysis of a Candida albicans pir32 null strain reveals proteins involved in adhesion, filamentation and virulence. [PDF]

PLoS ONE, 2018
We have previously characterized Pir32, a Candia albicans cell wall protein that we found to be involved in filamentation, virulence, chitin deposition, and resistance to oxidative stress. Other than defining the cell shape, the cell wall is critical for
Pamela El Khoury, Andy Awad, Brigitte Wex, Roy A Khalaf   +3 more
doaj   +1 more source

Characterization of Carrot Cell Wall Protein

Plant Physiology, 1981
Antiserum was raised against a synthetic nona-peptide which was predicted to have considerable homology with the unhydroxylated, unglycosylated precursor of cell wall proteins from several plants. The antiserum is able to recognize the major cell wall protein of incubated carrot (Daucus carota) root discs which is produced when the discs are treated ...
openaire   +3 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Identification of sortase A (SrtA) substrates in Streptococcus uberis: evidence for an additional hexapeptide (LPXXXD) sorting motif [PDF]

, 2009
Sortase (a transamidase) has been shown to be responsible for the covalent attachment of proteins to the bacterial cell wall. Anchoring is effected on secreted proteins containing a specific cell wall motif toward their C-terminus; that for sortase A ...
Anderson N. G., Atrazhev A. M., Banks D. J., Barnett T. C., Bender M. H., Berge A., Bierne H., Boekhorst J., Bradley A. J., Burne R. A., Burne R. A., Calvo E., Chaneton L., Chung J. W., Cole J. N., Comfort D., Cordwell S. J., Dramsi S., Ferretti J. J., Fischetti V. A., Galperin M. Y., Gardy J. L., Gatlin C. L., Grandi G., Harmon R. J., Hillerton J. E., Holden M. T., Hoskins J., Hughes M. J., Janulczyk R., Kleerebezem M., Kruger R. G., Mazmanian S. K., Mazmanian S. K., Morsczeck C., Moshynskyy I., Nandakumar R., Navarre W. W., Navarre W. W., Pallen M. J., Perry A. M., Pucciarelli M. G., Race P. R., Rainard P., Rigel N. W., Rodriguez-Ortega M. J., Schneewind O., Scott J. R., Severin A., Smoot J. C., Taverna F., Taylor D. L., Taylor G. K., Tettelin H., Ton-That H., Ward P. N., Ward P. N., Wexler D. L., Wright A.   +58 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Development of a method for the extraction and analysis of grape skin proteins strongly bound to cell walls

OENO One, 2013
Aim: To better understand the protein composition of grape skin cell walls, we have developed a method to analyse the strongly bound cell wall proteins. Methods and results: The protocol was developed with grape skins at full maturity. The critical steps
Grégory Pasquier, Delphine Lapaillerie, Jean-William Dupuy, Anne-Marie Lomenech, Stéphane Claverol, Marc Bonneu, Laurence Geny, Pierre-Louis Teissedre, Bernard Donèche   +8 more
doaj   +1 more source

Identification of a lipoteichoic acid glycosyltransferase enzyme reveals that GW-domain containing proteins can be retained in the cell wall of Listeria monocytogenes in the absence of lipoteichoic acid or its modifications

, 2016
Listeria monocytogenes is a foodborne Gram-positive bacterial pathogen, and many of its virulence factors are either secreted proteins or proteins covalently or noncovalently attached to the cell wall.
Grundling, A, Karinou, E, Percy, M, Webb, A   +3 more
core   +1 more source

OLIgo mass profiling (OLIMP) of extracellular polysaccharides. [PDF]

, 2010
The direct contact of cells to the environment is mediated in many organisms by an extracellular matrix. One common aspect of extracellular matrices is that they contain complex sugar moieties in form of glycoproteins, proteoglycans, and/or ...
Gille, Sascha, Günl, Markus, Pauly, Markus   +2 more
core   +3 more sources