Results 101 to 110 of about 365,586 (305)

Developmental Systems and Animal Behaviour [PDF]

open access: yes, 2002
This is a critical notice of Evolution's Eye by Susan Oyama, focusing on developmental systems theory primarily in relation to the nature-nurture debates and the explanation of ...
Robert, Jason Scott
core  

Echinoderms : Focus on the Sea Urchin Model in Cellular and Developmental Biology

open access: yes, 2021
Echinoderms, a sister group of chordates, is a group of exclusively marine animals. TheEchinodermata is an ancient phylum dating to at least 450 million years old and includingmore than 10,000 extant species present throughout the world’s oceans. The modernechinoderms belong to five classes: Echinoidea (e.g., sea urchins and sand dollars),Asteroidea (e.
Pontheaux, Florian   +3 more
openaire   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Loss of FTO Antagonises Wnt Signaling and Leads to Developmental Defects Associated with Ciliopathies [PDF]

open access: yes, 2014
Common intronic variants in the Human fat mass and obesity-associated gene (FTO) are found to be associated with an increased risk of obesity. Overexpression of FTO correlates with increased food intake and obesity, whilst loss-of-function results in ...
Rosa Maria Roccasecca (519728)   +40 more
core   +1 more source

Precision multiplexed base editing in human cells using Cas12a-derived base editors

open access: yesNature Communications
Base editors enable the direct conversion of target nucleotides without introducing DNA double strand breaks, making them a powerful tool for creating point mutations in a human genome. However, current Cas9-derived base editing technologies have limited
Anabel Y. Schweitzer   +4 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Analysis of cellular transitions

open access: yes, 2018
3rd Spanish Conference of Molecular Cellular and Developmental Biology of Drosophila (2015)Trabajo presentado en la 3rd Spanish Conference of Molecular Cellular and Developmental Biology of Drosophila, delebrada en Begur, Girona, del 25 al 27 de ...
Casanova, Jordi
core  

Role of epigenetics in developmental biology and transgenerational inheritance [PDF]

open access: yes, 2011
The molecular mechanisms involved in developmental biology and cellular differentiation have traditionally been considered to be primarily genetic. Environmental factors that influence early life critical windows of development generally do not have the ...
Michael K. Skinner, Skinner, Michael K
core   +1 more source

Genome-wide discovery of structured noncoding RNAs in bacteria

open access: yesBMC Microbiology, 2019
Background Structured noncoding RNAs (ncRNAs) play essential roles in many biological processes such as gene regulation, signaling, RNA processing, and protein synthesis. Among the most common groups of ncRNAs in bacteria are riboswitches.
Shira Stav   +5 more
doaj   +1 more source

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