Results 141 to 150 of about 365,586 (305)

Single-Cell Omics in Animal Reproductive Biology: A Cellular and Molecular Atlas Across Developmental Stages

Insights in Animal Science
The cutting-edge technologies of single-cell omics have revolutionized the study of animal reproduction, enabling the visualization of cellular and molecular domains in organisms during various growth stages. This review presents a conceptual framework grounded in the latest developments from single-cell RNA sequencing (scRNA-seq), ATAC sequencing ...
Kamran Ahmad Nasir, null Sohaib Khan, null Hassan Abbas, null Kashif Raza Zaidi   +3 more
openaire   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

FEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

What can functional transcranial Doppler ultrasonography reveal about the cerebral lateralization of writing

FEBS Letters, EarlyView.
Which brain hemisphere controls writing? This review synthesizes all five functional transcranial Doppler studies of writing (handwriting and typing) published to date in adults and children. Right‐handers show left‐hemispheric dominance for the linguistic component of writing (written word generation), whereas findings for left‐handers remain ...
Marietta Papadatou‐Pastou
wiley   +1 more source

Systems biology in toxicology and environmental health

, 2015
Systems Biology in Environmental Health: From the Genome to the Epigenome brings a systems biological perspective to recent findings that link environmental exposures to human disease.
Fry, Rebecca C.
core  

Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease

FEBS Letters, EarlyView.
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim, Thi Thanh Mai Tran, Nakyung Kang, Min‐Woo Lee, Mihye Lee   +4 more
wiley   +1 more source

Mapping the Polarity Interactome

, 2018
Interactions between proteins are an essential part of biology, and the desire to identify these interactions has led to the development of numerous technologies to systematically map protein-protein interactions at a large scale.
Boxem, Mike, Ribeiro Pires, Helena, Sub Developmental Biology, Developmental Biology   +3 more
core  

Mapping the cellular basis of species differences in oxytocin and dopamine receptor expression in the vole nucleus accumbens

Scientific Reports
Oxytocin (Oxtr) and dopamine (Drd1, Drd2) receptors provide a canonical example for how differences in neuromodulatory receptors drive individual and species-level behavioral variation. These systems exhibit striking and functionally relevant differences
Meredith K. Loth, Julia C. Schmidt, Cassandra A. Gonzalez, Liza E. Brusman, Julie M. Sadino, Kelly E. Winther, David S. W. Protter, Zoe R. Donaldson   +7 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Genetic perspectives on the ascidian central nervous system

Invertebrate Survival Journal, 2009
In 2002, date of publication of the Ciona intestinalis genome, ascidians entered the post-genomic era. This tool had a fundamental role and has become the starting point for a series of new functional and genomic studies.
A Locascio, F Ristoratore, A Spagnuolo, L Zanetti, M Branno   +4 more
doaj  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source