Results 81 to 90 of about 341,348 (303)
International plant molecular biology: a bright future for green science
, 2012 Sibum Sung, Enamul Huq and Z Jeffrey Chen* Author Affiliations Section of Molecular Cell and Developmental Biology, Center for Computational Biology and Bioinformatics, and Institute for Cellular and Molecular Biology, The University of Texas at ...
Sung, Sibum +2 more
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miR-1/206 downregulates splicing factor Srsf9 to promote C2C12 differentiation
Skeletal Muscle, 2019 Background Myogenesis is driven by specific changes in the transcriptome that occur during the different stages of muscle differentiation. In addition to controlled transcriptional transitions, several other post-transcriptional mechanisms direct muscle ...
Kristen K. Bjorkman +4 more
doaj +1 more source
Gene and library synthesis without amplification: polymerase step reaction (PSR)
BioTechniques, 2015 Current gene synthesis methods often incorporate a PCR amplification step in order to yield final material sufficient for resolution from multiple off-products. These amplification steps can cause stochastic sampling effects that propagate errors in gene
Zhuo-Bin Lee +3 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
"Riding with the Wnt": Investigating the role of Wnt signaling in cell migration
, 2018 During my PhD, my goal was to achieve a better understanding of how animals develop from embryogenesis to adulthood. Specifically, I studied how cells acquire and control their movement to sculpt the final shape of an organism.
Rella, Lorenzo, Developmental Biology
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Cell Reports: MethodsSummary: Polyphosphate (polyP) is a ubiquitous polyanion present throughout the tree of life. While polyP’s widely varied functions have been interrogated in single-celled organisms, little is known about the cellular distribution and function of polyP ...
Ellen Quarles +7 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Identification of novel factors that promote spindle positioning in the C. elegans embryo
, 2012 LIN-5, GPR-1/2, and the Ga proteins GOA-1 and GPA-16, have previously been identified as key regulators of spindle positioning. In this thesis we identified other components that contribute to the different spindle and nuclear positioning events in the ...
Sub Developmental Biology +3 more
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Breakthroughs and challenges of modern developmental biology and reproductive medicine
, 2019 In recent decades we have witnessed unprecedented progress in the field of the developmental biology of mammals. Building on 20 th century discoveries, we have managed to increase our understanding of the molecular and cellular mechanisms governing ...
Fishel, Simon +7 more
core +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source